{
  "abstract": "Background Robot-assisted surgery is becoming increasingly used in pediatric oncology. The present study aimed to evaluate the feasibility and safety of robotic liver resection (RLR) for hepatic focal nodular hyperplasia (FNH) in children and compare surgical outcomes between RLR and open liver resection (OLR).Methods Pediatric patients with liver FNH undergoing lesion resection between January 2020 and June 2024 were included in the study. Patient demographics, operative details, postoperative outcomes, and follow-up were recorded and analyzed.Results A total of 20 patients were included in this study. Twelve patients underwent RLR and eight underwent OLR. In the RLR group, the median age was 93.1 months (range, 28–134 months) with a median weight of 32.4 kg (range, 9.7–80 kg). The median maximum tumor diameter at operation was 62.6 mm (range, 49–80 mm) and the median tumor volume was 94.3 mL (range, 35–254.1 mL). Operative time was 168.5 min (range, 116–245 min), intraoperative blood loss was 23.3 mL (range, 5–50 mL) and the length of postoperative hospital stay was 5.7 days (range, 4–11 days). There was a significant difference ( p<0.05) between the RLR and OLR groups for: age (93.1 months vs. 137.6 months), maximum tumor diameter (62.6 mm vs. 98 mm), tumor volume (94.3 mL vs. 496.2 mL), operative time (168.5 min vs. 281.4 min), blood loss (23.3 mL vs. 288.7 mL), and length of postoperative hospital stay (5.7 days vs. 9.5 days). There was a borderline significant association between surgical approach (RLR/OLR) and fluctuation in the magnitude of Alanine aminotransferase (ALT) (odds ratio=0.004, 95% confidence interval: 0.000 to 1.096, p=0.05).Conclusions Our initial experience suggested that RLR for hepatic FNH in children was both feasible and safe. Tumors in the RLR group were significantly smaller than the OLR group: it proved possible to excise tumors larger than 250 mL in volume.",
  "authors": [
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Xuan Wu"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Min He"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Yinbing Tang"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Ming Chen"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Jiabin Cai"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Lifeng Zhang"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Yuwei Wang"
    },
    {
      "affiliations": [
        "Pediatric Cancer Research Center, National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Ting Tao"
    },
    {
      "affiliations": [
        "Department of Surgical Oncology, Children's Hospital, Zhejiang University School of Medicine,National Clinical Research Center for Child Health, Hangzhou, China",
        "Pediatric Cancer Research Center, National Clinical Research Center for Child Health, Hangzhou, China"
      ],
      "name": "Jinhu Wang"
    }
  ],
  "title": "Robotic liver resection for hepatic focal nodular hyperplasia in children: comparison with open surgery",
  "uid": "72fb0a7d-4852-560b-aa2c-bf854576c61b"
}