{
  "abstract": "A 13-year-old boy with primary ciliary dyskinesia (PCD) had progressive severe cystic bronchiectasis of the left middle and lower lobes on serial CT scans, in the context of situs inversus totalis and a trilobed left lung. He was chronically infected with Pseudomonas aeruginosa and Mycobacterium avium complex. Given the progressive nature of the bronchiectasis and declining clinical status, the decision was made to proceed to left middle and lower bilobectomy to prevent further destruction of the less diseased lung. To monitor outcomes, phase-resolved functional lung (PREFUL) MRI, spirometry and Lung Clearance Index (LCI) derived from multiple breath nitrogen washout (MBNW) were performed 1 week prior and 16 weeks after the bilobectomy. MRI examinations were performed on a 3T Siemens scanner during free breathing with no contrast agent administered. PREFUL processing was used to derive regional pulmonary ventilation and perfusion distribution from proton MRI data.1",
  "authors": [
    {
      "affiliations": [
        "Department of Respiratory Medicine, Sydney Children’s Hospital Randwick, Randwick, New South Wales, Australia",
        "Discipline of Paediatrics and Child Health, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia"
      ],
      "name": "Megan Frohlich"
    },
    {
      "affiliations": [
        "Division of Research and Enterprise, Research Imaging NSW, University of New South Wales, Sydney, New South Wales, Australia"
      ],
      "name": "Claudia Hillenbrand"
    },
    {
      "affiliations": [
        "Division of Research and Enterprise, Research Imaging NSW, University of New South Wales, Sydney, New South Wales, Australia",
        "Medical Imaging Department, Prince of Wales Hospital, Randwick, New South Wales, Australia"
      ],
      "name": "Sean Burke"
    },
    {
      "affiliations": [
        "Department of Respiratory Medicine, Concord Repatriation General Hospital, Sydney, New South Wales, Australia",
        "The University of Sydney Faculty of Medicine and Health, Sydney, New South Wales, Australia"
      ],
      "name": "Lucy Morgan"
    },
    {
      "affiliations": [
        "Department of Respiratory Medicine, Sydney Children’s Hospital Randwick, Randwick, New South Wales, Australia",
        "Discipline of Paediatrics and Child Health, University of New South Wales Medicine & Health, Sydney, New South Wales, Australia"
      ],
      "name": "Adam Jaffé"
    }
  ],
  "title": "Phase-resolved functional lung (PREFUL) MRI provides unique insight into response to bilobectomy in a child with primary ciliary dyskinesia",
  "uid": "52289a22-32c8-5448-9ffc-fd3d3582e88f"
}