{
  "abstract": "Background Social determinants have been associated with adverse outcomes in asthma. The literature suggests particular roles for race/ethnicity and socioeconomic status (SES) 1 2. However, the vast majority of this work is from North America, which may limit its applicability in other contexts.This systematic review aimed to summarise the literature specific to the United Kingdom (UK) with a long-term view of informing locally applicable intervention/policy development.Methods Searches were conducted in July 2023 and updated in April 2024. Studies were identified from Ovid Embase, Ovid MEDLINE and Web of Science from 1998 onwards. Included studies examined objectives related to UK minority ethnicity (UKME) and/or SES in adult asthma in the UK.Citations were managed using www.covidence.org. Screening, extraction and quality assessment were undertaken by a team of reviewers. Data were extracted using a priori criteria adapted on review of initial studies.The study was registered in PROSPERO.Results An examination of over 25 years of the UK literature found 23 studies assessing the impact of UKME and/or SES on asthma outcomes. Studies had inconsistent ways of assessing outcomes and potential mediating factors.Of six studies assessing the impact of UKME on asthma hospitalisations, four found an increased risk of hospitalisation associated with UKME. All five studies assessing the impact of SES found an increased risk of hospitalisation associated with low SES.Conclusion The UK literature suggests that UKME and SES are associated with asthma hospitalisations. A greater understanding of precisely which groups are most affected, in what contexts and through which mediating factors is required to effectively translate established knowledge into effective service and policy interventions.References Akin-Imran A, Bajpai A, McCartan D, Heaney LG, Kee F, Redmond C, et al. Ethnic variation in asthma healthcare utilisation and exacerbation: systematic review and meta-analysis. ERJ Open Research 2023;9(3).Redmond C, Akinoso-Imran AQ, Heaney LG, Sheikh A, Kee F, Busby J. Socioeconomic disparities in asthma health care utilization, exacerbations, and mortality: a systematic review and meta-analysis. The Journal of Allergy and Clinical Immunology 2022;149(5):1617–27.",
  "authors": [
    {
      "affiliations": [
        "NIHR Nottingham Respiratory BRC, Nottingham, UK"
      ],
      "name": "I Adejumo"
    },
    {
      "affiliations": [
        "Nottingham University Hospitals NHS Trust, Nottingham, UK"
      ],
      "name": "S Chandrasekharan"
    },
    {
      "affiliations": [
        "University of Nottingham Medical School, Nottingham, UK"
      ],
      "name": "E Barber"
    },
    {
      "affiliations": [
        "University of Nottingham Medical School, Nottingham, UK"
      ],
      "name": "A De"
    },
    {
      "affiliations": [
        "Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK"
      ],
      "name": "CV Chalitsios"
    },
    {
      "affiliations": [
        "Translational Medical Sciences, University of Nottingham, Nottingham, UK"
      ],
      "name": "J Kaur"
    },
    {
      "affiliations": [
        "Diabetes Research Centre, University of Leicester, Leicester, UK"
      ],
      "name": "W Ekezie"
    },
    {
      "affiliations": [
        "NIHR Nottingham Respiratory BRC, Nottingham, UK"
      ],
      "name": "TM McKeever"
    },
    {
      "affiliations": [
        "University of Leicester, Leicester, UK"
      ],
      "name": "DE Shaw"
    }
  ],
  "title": "P64 Assessing the effect of ethnicity and socioeconomic status on outcomes in asthma: a systematic review",
  "uid": "be855aa5-1e1c-545d-9779-d576b97cf9fc"
}