{
  "abstract": "Introduction and Objectives Severe asthma (SA) affects a minority of asthma patients but has a disproportionately high impact on quality of life. Despite advances in biologic therapies, patients still face significant daily burdens. Little is known about how patients perceive their care, including their understanding of the concept of clinical remission (CR). This study explored the lived experience of people with SA receiving biologic therapy and identified perceived gaps in care.Methods On behalf of GSK, Ipsos conducted a 10-minute online survey among 100 UK adults with SA. Participants were recruited via Asthma+Lung UK and online panels. This analysis focuses on the 75 patients currently receiving biologics (67% [n=50] female, mean age 49 years, regionally diverse). The survey explored symptom burden, care experiences, treatment goals, and familiarity with the concept of CR.Results Breathlessness (62%; n=44) and low energy (54%; n=38) were reported as the most burdensome symptoms. Over half of patients indicated SA negatively impacted key areas of life ( figure 1). One in four expressed ongoing worry about their condition, and one in five reported struggling to cope. Experiences of care varied, with challenges noted in accessing and managing treatment. Over half (61%; n=46) were unfamiliar with the term CR, though 55% (n=41) considered it achievable and 95–97% (n=71–73) recognised the importance of treatment goals that define it. A majority (77%; n=58) felt it was very important that healthcare professionals discuss treatment goals as part of shared decision-making. Respiratory consultants/specialists (64%; n=48), specialist nurses (51%; n=38) and GPs (45%; n=34) were the most valued sources of support. However, some patients reported dissatisfaction with diagnostic delays (24%; n=18), referral speed (19%; n=14), and information provision (19%; n=14).Abstract P118 Figure 1Proportion of patients reporting a negative impact of severe asthma on different areas of lifeConclusions SA continues to place a significant emotional burden and practical limitation on patients’ lives. Individual markers of CR are seen as attainable goals, yet awareness of the concept itself is limited. Patients value shared decision-making and support from specialists, but gaps in care persist. These findings highlight the need for more consistent, patient-centred care prioritising mental health, timely access to services, and meaningful patient engagement through improved communication, education, and shared decision-making.",
  "authors": [
    {
      "affiliations": [
        "GlaxoSmithKline, London, UK"
      ],
      "name": "V Patel"
    },
    {
      "affiliations": [
        "University Hospital Southampton NHS Foundation Trust, Southampton, UK"
      ],
      "name": "H Rupani"
    },
    {
      "affiliations": [
        "Queen’s University Belfast, Belfast, UK"
      ],
      "name": "LG Heaney"
    },
    {
      "affiliations": [
        "Royal Brompton and Harefield Hospitals, London, UK"
      ],
      "name": "P Patel"
    },
    {
      "affiliations": [
        "Mid Yorkshire Hospitals NHS Trust, Leeds, UK"
      ],
      "name": "L Jones"
    },
    {
      "affiliations": [
        "GlaxoSmithKline, London, UK"
      ],
      "name": "M Moore"
    },
    {
      "affiliations": [
        "Ipsos, London, UK"
      ],
      "name": "D Montalto"
    },
    {
      "affiliations": [
        "Ipsos, London, UK"
      ],
      "name": "G Turley"
    },
    {
      "affiliations": [
        "Asthma and Lung UK, London, UK"
      ],
      "name": "A Fynney"
    },
    {
      "affiliations": [
        "Asthma and Lung UK, London, UK"
      ],
      "name": "A Whittamore"
    }
  ],
  "title": "P118 Understanding the experience and unmet needs of patients living with severe asthma on biologic therapy; including views on clinical remission",
  "uid": "8b27083b-9a3f-57e3-bb01-8c3df26441b5"
}