{
  "abstract": "Introduction Estimates suggest that thousands of patients across the UK, unknown to secondary care, are eligible for asthma biologic therapy. 1 This includes underserved populations who are at risk of poorer asthma outcomes. Many GP practices do not have a method of identifying such patients.2 Case-finding programmes can be burdensome for overstretched primary care services and have previously struggled with patient engagement with secondary care.Aim To assess the impact of a physician-led community asthma biologic screening programme.Methods A data sharing agreement was signed with a Bristol GP collaborative who conducted a search in January 2025 across 33 practices using the criteria: 18+ years, asthma diagnosis, without prescription of asthma biologic, 3+ prednisolone prescriptions and an inhaled corticosteroid in the last year and eosinophil count ≥0.3 in the last two years. Electronic healthcare records were screened by a registrar or consultant to assess suitability for clinical review. Patients received a letter and telephone call to confirm suitability, invite them to the appointment, and address barriers to clinic attendance.Results 433 patients were identified from the search. 97/433(22%) were deemed potentially eligible for asthma biologics ( figure 1). 69 patients agreed to attend clinic. To date, 57 of these appointments are complete. 15/57(26%) patients were discussed at the complex airways MDT with 12 patients starting asthma biologics. 33/57(58%) patients received optimisation of asthma care, referral for diagnostics and/or allied health professional review, with 26 to have follow-up. 2 patients were discharged without intervention and 6 due to non-attendance.Abstract P70 Figure 1Consort diagram from patient identification to first clinic completionConclusion We demonstrate a pragmatic respiratory physician-led community screening programme for uncontrolled severe asthma. Most patients seen in clinic benefitted from treatment optimisation and 21% of patients reviewed have commenced biologic therapies - this proportion is likely to increase after follow-up clinics. An important success was the high clinic attendance rate, a barrier that we anticipated and overcame with our project design. Further work is required to expand this project to other practices and consider other asthma phenotypes.References Rupani, et al. ERJ. 2024;64(Suppl 68):PA4487.Accelerated Access Collaborative. Understanding opportunities to improve Severe Asthma Care in England. A National Benchmarking Exercise.2022 [https://www.healthinnovationoxford.org/wp-content/uploads/2022/03/Severe-Asthma-Benchmarking-Summary-of-Findings-1.pdf,accessed 19/6/25]",
  "authors": [
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "GW Nava"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "H Sakota"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "CR Morgan"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "JS Grenville"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "DH Higbee"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "JW Dodd"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "R Shrimanker"
    },
    {
      "affiliations": [
        "North Bristol Lung Centre, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "PW Creber"
    }
  ],
  "title": "P70 Asthma biologic case-finding, an evaluation of a pragmatic physician-led community screening programme within bristol complex airways service",
  "uid": "3a7b6165-b068-5018-a256-7b5c154e5832"
}