{
  "abstract": "The 13-valent conjugate pneumococcal vaccine (13vPCV) replaced the 7vPCV in the Australian Immunisation Program in 2011 as a 3+0 schedule, updated to 2+1 schedule in 2018. We analysed national surveillance data to investigate the change in the incidence of pneumococcal serotype 3 (ST3) invasive pneumococcal disease (IPD) in preschool children. During 2009–2023 the incidence/100 000 children of ST3 IPD increased from 0.42 in 2009 to 3.65 in 2023. Compared with 2009–2011 (7vPCv), ST3 IPD incidence in 2012–2018 (13vPCV 3+0 dose) was almost four times higher and two times higher in 2019–2023 (13vPCV 2+1 dose) compared with 2012–2018 suggesting limited protection against ST3.",
  "authors": [
    {
      "affiliations": [
        "Discipline of Paediatrics and Child Health, School of Clinical Medicine, University of New South Wales (UNSW), Sydney, New South Wales, Australia",
        "Department of Respiratory Medicine, Sydney Children’s Hospital, Sydney, New South Wales, Australia"
      ],
      "name": "Nusrat Homaira"
    },
    {
      "affiliations": [
        "Discipline of Paediatrics and Child Health, School of Clinical Medicine, University of New South Wales (UNSW), Sydney, New South Wales, Australia"
      ],
      "name": "Jahidur Rahman Khan"
    },
    {
      "affiliations": [
        "Discipline of Paediatrics and Child Health, School of Clinical Medicine, University of New South Wales (UNSW), Sydney, New South Wales, Australia",
        "Department of Respiratory Medicine, Sydney Children’s Hospital, Sydney, New South Wales, Australia"
      ],
      "name": "Adam Jaffé"
    }
  ],
  "title": "Serotype 3 associated invasive pneumococcal disease in children: analysis of 15 years of Australian national surveillance data",
  "uid": "796101de-1a48-556e-a351-2a9500a6fe00"
}