{
  "abstract": "Rates of fluconazole-resistant Candida albicans and non-C. albicans yeasts are increasing in the UK. In Leeds, between 2018–2019 and 2020–2021, the percentage of non-C. albicans yeasts rose from 6.0% to 12.6% and fluconazole dose-dependent/resistant isolates increased from 3.5% to 9.6%.1 Prolonged courses of self-purchased antifungals,2 and presumptive diagnoses with inappropriate empirical treatment,1 have been associated with fluconazole resistance. Clinical symptoms and signs of vulvovaginal candidiasis (VVC) are non-specific, and empirical antifungal prescribing results in over 50% of antifungals being ineffective or unnecessary.3",
  "authors": [
    {
      "affiliations": [
        "Genitourinary Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, UK"
      ],
      "name": "Janet D Wilson"
    }
  ],
  "title": "Managing persistent and recurrent candidiasis due to fluconazole-resistant Candida albicans and non-Candida albicans yeasts",
  "uid": "ca8d6a2c-71a3-564e-a733-4babcb587b5f"
}