{
  "abstract": "Advanced HIV disease (AHD)—defined by a CD4 count <200 cells/mm 3—is associated with poor health outcomes. This study used household surveys from 13 countries in Sub-Saharan Africa to estimate the proportion of all people with AHD in the region. Among 28 040 surveyed people with HIV (65% female, median age 38, 53% resident in rural areas), AHD was found in nearly 10% (n=2261). AHD was associated with male sex and older age but not with rural versus urban location or economic status. Based on HIV prevalence data, nearly 2 million people were estimated to have AHD in Sub-Saharan Africa. The findings highlight the continued need for comprehensive HIV care alongside antiretroviral therapy provision in the region.",
  "authors": [
    {
      "affiliations": [
        "Department of Genitourinary Medicine and Infectious Diseases, St James’s Hospital, Dublin, Ireland"
      ],
      "name": "Giovanni Villa"
    },
    {
      "affiliations": [
        "Infectious Diseases, Burjeel Hospital, Abu Dhabi, UAE"
      ],
      "name": "Rachel Herbert"
    },
    {
      "affiliations": [
        "Lawson Unit, University Hospitals Sussex NHS Foundation Trust, Brighton, UK"
      ],
      "name": "Sonia Raffe"
    },
    {
      "affiliations": [
        "Infectious Diseases Unit, University of Rome Tor Vergata, Roma, Italy"
      ],
      "name": "Drieda Zace"
    }
  ],
  "title": "Research news in clinical context",
  "uid": "ee465c96-702e-5b0a-bde4-9e60ebe7dbff"
}