{
  "abstract": "Investigator-initiated clinical trials (IITs) are at the core of innovative thinking in health research generating data in real-world settings that influence global policy. Although diminished funding and a reduced workforce pose significant challenges, IITs should be championed as the best model to deliver unbiased, independent health research.",
  "authors": [
    {
      "affiliations": [
        "NIHR Leeds Biomedical Research Centre, The Leeds Teaching Hospitals NHS Trust, Leeds, England, UK",
        "Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, England, UK"
      ],
      "name": "Helena Marzo-Ortega"
    },
    {
      "affiliations": [
        "NIHR Leeds Biomedical Research Centre, The Leeds Teaching Hospitals NHS Trust, Leeds, England, UK",
        "Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, England, UK"
      ],
      "name": "Gabriele De Marco"
    }
  ],
  "title": "Are investigator-initiated clinical trials becoming an ‘endangered species’?",
  "uid": "d2909f9a-39cd-5ba6-832e-4a3dca0b718b"
}