{
  "abstract": "Spinal anesthesia is a safe, well-established analgesic technique that offers several advantages over general anesthesia, particularly for ambulatory surgeries. Spinal anesthesia can avoid airway manipulation and is known to be hemodynamically stable.1 Among short-acting local anesthetics, 2-chloroprocaine is a rapidly metabolized amino-ester increasingly used in adult ambulatory practice. It has been employed for continuous postoperative epidural infusions in neonates and infants.2 The safety profile of 2-chloroprocaine is favorable: systemic toxicity effects reported in infants have been self-limited with no long-term sequelae, and adult studies show shorter post-anesthesia care times compared with lidocaine without increasing transient neurologic symptoms.3 4 Currently, no studies characterize single-shot 2-chloroprocaine spinal use in children. As such, this is the first large institutional experience reporting dosing ranges for single-shot spinal 2-chloroprocaine for pediatric and adolescent orthopedic surgery.",
  "authors": [
    {
      "affiliations": [
        "Icahn School of Medicine at Mount Sinai, New York, New York, USA",
        "Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York, USA"
      ],
      "name": "Renee Ren"
    },
    {
      "affiliations": [
        "Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York, USA"
      ],
      "name": "Periklis Giannakis"
    },
    {
      "affiliations": [
        "Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York, USA"
      ],
      "name": "Alex Illescas"
    },
    {
      "affiliations": [
        "Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York, USA",
        "Orthopaedics / Population Health Science & Policy, Hospital for Special Surgery, New York, New York, USA"
      ],
      "name": "Jashvant Poeran"
    },
    {
      "affiliations": [
        "Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York, USA",
        "Department of Anesthesia, Weill Cornell Medicine, New York, New York, USA"
      ],
      "name": "Kathryn DelPizzo"
    },
    {
      "affiliations": [
        "Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, New York, USA",
        "Department of Anesthesia, Weill Cornell Medicine, New York, New York, USA"
      ],
      "name": "Michelle Carley"
    }
  ],
  "title": "Spinal 2-chloroprocaine for pediatric orthopedic surgery: a retrospective dosing analysis by age, weight, and procedure",
  "uid": "e868c63b-5310-5de1-9727-05d540e7d29d"
}