{
  "abstract": "The Letter by Rousseleau et al1 raises the appropriate next question: when does bupivacaine detected beyond a fascial plane become pharmacodynamically relevant? Our experiments were not designed to answer that clinical question directly. They addressed a preceding problem in anatomical spread studies: whether methylene blue or iodinated contrast can be used as reliable substitutes for the tissue distribution of bupivacaine. Our data indicate that they cannot.",
  "authors": [
    {
      "affiliations": [
        "Faculty of Medicine, Institute of Anatomy, University of Ljubljana, Ljubljana, Slovenia",
        "Jafral d.o.o, Ljubljana, Slovenia"
      ],
      "name": "Simon Istenič"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Institute of Anatomy, University of Ljubljana, Ljubljana, Slovenia"
      ],
      "name": "Luka Pušnik"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Institute of Anatomy, University of Ljubljana, Ljubljana, Slovenia"
      ],
      "name": "Chiedozie Kenneth Ugwoke"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Institute of Anatomy, University of Ljubljana, Ljubljana, Slovenia"
      ],
      "name": "Nejc Umek"
    }
  ],
  "title": "Bupivacaine distribution, tracer visibility, and clinical effect",
  "uid": "67597376-269b-52a9-95de-23769e6b9e03"
}