{
  "abstract": "Shing et al evaluated the analgesic efficacy of muscle relaxants in patients with fibromyalgia and included 14 randomized controlled trials (n=1851 participants). Muscle relaxants were associated with a small, yet statistically significant, reduction in pain scores, compared with placebo or active treatment. There was no significant inconsistency (I² = 0, 95% CI 0% to 50.79%), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) rating was moderate. Secondary outcomes showed small but statistically significant improvements in depression, fatigue, and sleep quality. However, muscle relaxants were associated with an increased incidence of overall adverse effects, fatigue, abnormal taste, and drug withdrawal due to adverse effects. The authors concluded that moderate-quality evidence showed muscle relaxants were associated with a small reduction in pain intensity for patients with fibromyalgia.1",
  "authors": [
    {
      "affiliations": [
        "Federal University of São Carlos (UFSCar), São Carlos, SP, Brazil"
      ],
      "name": "André Pontes-Silva"
    }
  ],
  "title": "Are we relaxing muscles or lowering standards? Interpreting pharmacological effects in fibromyalgia",
  "uid": "48a2e561-124d-5bf0-b515-3b2e85155f5e"
}