{
  "abstract": "Please confirm that an ethics committee approval has been applied for or granted: Yes: I’m uploading the Ethics Committee Approval as a PDF file with this abstract submissionApplication for ESRA Abstract PrizesBackground and Aims Subarachnoid block (SAB) is commonest method for caesarean section (CS). Conventionally, opioids are mixed with hyperbaric bupivacaine in a single syringe before administration. Sequential technique involves administration of these drugs via separate syringes. Significant hypotension is caused after SAB, however, Sequential technique has been shown to cause less hypotension.Methods A Prospective Randomized Interventional Comparative study was done with 180 parturients for 18 months undergoing elective CS under SAB. The participants were randomized by computer generated sequence into two groups of 90 each, group M and S. Group M (mixture) received 0.5% hyperbaric bupivacaine 9 mg (1.8 ml) with fentanyl 15 mcg (0.3 ml) in a single syringe, while S (sequential) received both drugs in separate syringes. The objective of the study was to test the efficacy of SAB in by block characteristics, hemodynamics and time to achieve sensory block height (T5).Results The study showed that Parturients in group S had higher level of sensory block & high modified Bromage score (MBS) than in group M. The median time to achieve T5 level in group S was less. The median sensory block duration of patients in group S was longer. The difference between two groups was highly significant. The mean time of two segment regression of block was longer in group S.Abstract P303 Figure 1Ethical committee letterConclusions The study concluded that sequential technique of giving drugs for SAB in C- section reduces the time to achieve complete sensory and motor block and delays block regression. Incidence of hypotension was low in both the groups.",
  "authors": [
    {
      "affiliations": [
        "Anaesthesiology, Max Superspecialty Hospital, Saket, New Delhi, India"
      ],
      "name": "Rahul Kalshan"
    },
    {
      "affiliations": [
        "Anaesthesiology, ESIC Medical College and Hospital, Ghaziabad, India"
      ],
      "name": "Apoorva Singh"
    },
    {
      "affiliations": [
        "Anaesthesiology, VMMC and Safdarjung Hospital, New Delhi, India"
      ],
      "name": "Ranju Gandhi"
    }
  ],
  "title": "P303 Comparative study of hyperbaric bupivacaine and fentanyl given either as a mixture or sequentially for subarachnoid block in parturients",
  "uid": "f948baf4-8fed-5fec-baf9-8e3e14d62589"
}