{
  "abstract": "Background and Aims Studies have demonstrated sheath surrounding the sciatic nerve is different from the epineurium and injection inside the sheath can be differentiated from an intraneural injection. Objectives: 1. To evaluate the existence of three separate compartment and investigate the spread pattern of the injected dye. 2. To identify the pathways from three compartments towards the nerve fascicles and the compartment injection in closest approximation to the fascicle 3. To evaluate the intra-muscular, vascular and neural diffusion.Methods In 6 Theil embalmed cadavers (12 specimens) in the prone position, Ultrasound guided injections were performed with 10 ml latex dye in three compartments; the sub-epimyseal (SEmyC), the sub- paraneural(SPC) and the sub-epineural compartment (SEpiC) of sciatic nerve. Each injection in 2 specimens. Yellow dye- SEmyC; Green dye- SPC; Blue dye- SEpiC After 2 weeks, upon cross-sections at two levels, one at the level of sciatic foramen and the second at the level of the greater trochanter and ischial tuberosity. Images were obtained and analyzed.Results The SEmyC injections revealed the yellow latex occupying the entire intra-muscular compartment and no spread towards neural elements. In the SPN injection, the green latex was visualized in the intra-muscular compartment, the paraneural adipose tissue at the level of the sciatic foramen and in close approximation with sacral rami. In the SEpiC, the blue latex occupied adipose tissue beneath the epineurium and highlighted the fascicular components. However, no dye was visible inside the fascicle.Abstract OP41 Figure 1Cross sections of human cadaverConclusions Based on our cadaveric study, it is becoming evident the adipose tissue in the SPC and the SEpiC is gaining prime importance for the pathways towards the sciatic nerve in reaching the fascicles. The SEpiC injections reliably engulf the fascicles and perhaps with low volumes, but depends on the amount of adipose tissue in the compartment.",
  "authors": [
    {
      "affiliations": [
        "Anaesthesia, Private, Pune, India"
      ],
      "name": "Sandeep Diwan"
    },
    {
      "affiliations": [
        "Anaesthesia, Private, Nagpur, India"
      ],
      "name": "Rasika Timane"
    }
  ],
  "title": "OP41 Optimal injection sites: sub-epimyseal, sub-paraneural or sub-epineurial? At the level of greater trochanter",
  "uid": "ef3f772a-ceae-57c8-bdd3-debf96be7b56"
}