{
  "abstract": "Background and Aims Complex Regional Pain Syndrome (CRPS) is a chronic pain condition triggered by injury or surgery. It presents as Type 1 (no nerve injury) or Type 2 (with nerve injury) and is marked by prolonged, severe pain. We report the yearly incidence of CRPS and describe inpatient procedures occurring up to one year before initial CRPS diagnosis.Methods This retrospective cohort study used 2019–2022 Merative MarketScan (IRB# 2017–0169) data, representing commercially insured patients in the US. We identified patients with an initial CRPS diagnosis (ICD-10: G90.5x, G56.4x, G57.7x) among adults (18+) and pediatric (<18) patients. Yearly rates of CRPS diagnoses per 100,000 patients were calculated. Subsequently, we identified inpatient surgical procedures that occurred ≤1 year before an initial CRPS diagnosis.Results Between 2019 and 2022, we identified 24,522 and 1,333 new CRPS diagnoses among adults and pediatric patients from the general population, respectively. From 2019 to 2022, the yearly incidence of CRPS diagnoses decreased from 42.7 per 100,000 patients to 35.9 among adults and from 8.3 per 100,000 patients to 6.4 among pediatric patients ( figure 1). There were 3,346 (1,399 musculoskeletal) adults and 104 (40 musculoskeletal) pediatric patients with an inpatient procedure within the year prior of their diagnosis, suggesting that surgery is a probable inciting event in 13.6% of new adult CRPS cases, and 7.8% of new CRPS cases in younger patients.Abstract OP31 Figure 1Yearly incidence of CRPS in adult (18+ years old) and pediatric (Conclusions We report a downward trend in new CRPS diagnoses among both adults and pediatric patients, along with an overview of procedures within the year prior that may have led to the condition. These findings may provide valuable insight into the diagnosis of this condition. Further research is needed to determine if certain procedures are more likely to induce CRPS and how these patterns differ between adults and pediatric patients.",
  "authors": [
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "Alex Illescas"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "Tina Chen"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "William Chan"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "Daniel Richman"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA",
        "Department of Anesthesiology, Weill Cornell Medicine, New York, USA",
        "Department of Health Policy and Research, Weill Cornell Medical College, New York, USA"
      ],
      "name": "Stavros Memtsoudis"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "Alexandra Sideris"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "Jashvant Poeran"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA"
      ],
      "name": "Semih Gungor"
    }
  ],
  "title": "OP31 Yearly incidence of complex regional pain syndrome in adult and pediatric patients in the United States: an analysis using the merative marketscan database",
  "uid": "ec848684-c0f2-5975-bda7-b77effb7783e"
}