{
  "abstract": "Please confirm that an ethics committee approval has been applied for or granted: Yes: I’m uploading the Ethics Committee Approval as a PDF file with this abstract submissionBackground and Aims In recent years, both SII and SIRI have been reported as prognostic predictors in various diseases. We retrospectively investigated the association between SII, SIRI, and postoperative analgesia in MIDCAB patients who underwent TRLPVB.Methods A retrospective cohort study was conducted on the medical records of 23 patients who underwent MIDCAB from August 2017 to November 2023 in a single hospital. After the induction of anesthesia, a single-shot TRLPVB was performed at 2 to 4 vertebral levels in all cases, using 40 cc of ropivacaine at concentrations ranging from 0.25% to 0.5%, centered on the intercostal space planned for thoracotomy. Preoperatively and intraoperatively, none of the patients received any analgesics other than local anesthetics, fentanyl, or remifentanil. The values of SII and SIRI were calculated from both preoperative and postoperative laboratory data immediately after ICU admission, including segmental neutrophil count, monocyte count, lymphocyte count, and platelet count (PreSII, PreSIRI, PostSII, and PostSIRI). For each the values (SII and SIRI), the difference in values before and after surgery was denoted as ΔSII and ΔSIRI (ΔSII=PostSII-PreSII, ΔSIRI=PostSIRI-PreSIRI), respectively. All patients were divided into two groups: those who required analgesics after extubation (R group) and those who did not require any analgesics (N group). A comparative analysis was conducted on PreSII, PreSIRI, ΔSII, and ΔSIRI values between the two groups.Results After excluding 8 patients, the study included 6 in the N group and 9 in the R group. There were no significant differences between the two groups in terms of age, sex, BMI, one-lung ventilation time, anesthesia time, surgical time, and intraoperative consumption of remifentanil and fentanyl. The PreSII values in the N group were significantly lower compared to those in the R group (p=0.0184).Conclusions High PreSII values were identified as potential predictors of increased postoperative analgesic requirements following MIDCAB surgery using single-shot multi-level TRLPVB.",
  "authors": [
    {
      "affiliations": [
        "Department of Anesthesiology, Chigasaki Tokushukai Hospital, Chigasaki, Japan"
      ],
      "name": "Hirotaka Ito"
    }
  ],
  "title": "P061 The perioperative systemic immune-inflammation index predicts postoperative analgesic requirements following MIDCAB surgery with single-shot multi-level thoracic retrolaminar paravertebral block (TRLPVB): a single-center retrospective study",
  "uid": "a9a48131-b1a4-5aa7-937f-b632755ae31d"
}