{
  "abstract": "Background and Aims With global aging, the demand for joint replacement surgery has increased and many factors affect postoperative complications. However, the relationship between anesthetic techniques and postoperative complications following unilateral total joint arthroplasty (TJA) remains unclear. This study aimed to assess the impact of general anesthesia (GA) versus non-general anesthesia (non-GA) on the length of postoperative stay (LOS) and other secondary outcomes in patients undergoing unilateral TJA.Methods This observational retrospective cohort study included 4518 patients (≥65 years) who underwent unilateral TJA at the First Medical Center of the Chinese People’s Liberation Army General Hospital between January 2014 and December 2021. The primary outcome was length of postoperative stay. Secondary outcomes included postoperative complications such as delirium, operative area infection, stroke, myocardial infarction, acute kidney injury (AKI), myocardial injury following non-cardiac surgery (MINS), admission to the intensive care unit (ICU) and one-year mortality. To investigate the effect of anesthetic techniques, univariate, multivariate, propensity score matching (PSM), and inverse probability of treatment weighting (IPTW) analyses were performed.Results The study included 4518 patients, with 2708 receiving GA and 1810 not receiving GA.. GA was associated with a shorter hospital stay than non-GA (-0.43 days, 95% CI: -0.71 to − -0.14, P = 0.003). After adjusting for confounding factors using PSM and IPTW, the length of hospital stay was reduced in the GA group compared to that in the non-GA group (-0.61, 95%CI: -0.93, -0.29, P < 0.001 in PSM; -0.52, 95%CI: -0.79, -0.25, P < 0.001 in IPTW). There were no significant differences between the two groups in terms of other postoperative complications or mortality after unilateral TJA.Conclusions General anesthesia significantly shortened the postoperative stay of elderly patients undergoing unilateral TJA without increasing the risk of postoperative complications. These results provide a valuable reference for anesthesiologists, surgeons, and patients when making decisions regarding anesthesia selection.",
  "authors": [
    {
      "affiliations": [
        "Department of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Bejing, China"
      ],
      "name": "Zhuoning Zhang"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, The First Medical Center of Chinese PLA General Hospital, Bejing, China"
      ],
      "name": "Siyi Yao"
    }
  ],
  "title": "EP116 Perioperative complications after unilateral total joint arthroplasty in elderly patients under general anesthesia versus non-general anesthesia: a matched-pair cohort analysis",
  "uid": "2db25436-c018-5e2e-ac5a-6ccd3d60ba64"
}