{
  "abstract": "Background and Aims Spinal anesthesia is often preferred for cesarean surgery. As hemodynamic stability is crucial during cesarean sections, this study compares the effects of intrathecal dexmedetomidine combined with bupivacaine versus bupivacaine alone on hemodynamic changes and postoperative pain management in pregnant women undergoing cesarean sections under spinal anesthesia.Methods A double-blind, randomized clinical trial involving 82 pregnant women undergoing cesarean surgery compared dexmedetomidine-bupivacaine (intervention) and bupivacaine alone (control). Patients were randomly assigned to groups using a block method. Hemodynamic parameters (systolic blood pressure, diastolic blood pressure, and heart rate) were measured at 1, 3, 5, 30, and 60 minutes during surgery.Results The average patient age was 29.41±4.75 years (n=82). Surgery duration averaged 158.78±19.26 minutes in the intervention group and 127.31±23.02 minutes in the control group. Systolic and diastolic blood pressure did not differ significantly between the dexmedetomidine-bupivacaine and bupivacaine-only groups at times 1, 3, 5, 30, and 60 minutes during surgery. Dexmedetomidine prolonged pain control compared to the control group (P=0.02). Heart rate did not differ significantly between groups at times 1, 3, and 60 minutes, but was significantly lower in the dexmedetomidine-bupivacaine group at times 5 (P=0.03) and 30 minutes (P=0.001).Conclusions This study found no difference in systolic or diastolic blood pressure between the two groups. However, dexmedetomidine-bupivacaine significantly impacted heart rate at 5 and 30 minutes during cesarean surgery and improved postoperative pain management. Further research in this area is recommended.",
  "authors": [
    {
      "affiliations": [
        "Anesthesiology and Critical Care Medicine, Golestan University of Medical Sciences (GoUMS), Panjom Azar, Gorgan City, Islamic Republic of Iran"
      ],
      "name": "Ali Jabbari"
    },
    {
      "affiliations": [
        "Anesthesiology and Critical Care Medicine, Golestan University of Medical Sciences (GoUMS), Panjom Azar, Gorgan, Islamic Republic of Iran"
      ],
      "name": "Mansour Deylami"
    }
  ],
  "title": "EP044 Intrathecal dexmedetomidine effects on hemodynamics and postoperative pain in pregnant women undergoing cesarean section with spinal anesthesia",
  "uid": "29a8fac4-bd05-557e-a5aa-d782930e9fc7"
}