{
  "abstract": "Despite the availability of several decades of studies, the question of whether use of regional anesthesia offers superior outcomes for patients in the perioperative setting when compared with general anesthesia remains unresolved. We still do not have a definitive answer to whether regional anesthesia is superior to general anesthesia in improving perioperative patient outcomes. While the majority of larger meta-analyses and database analyses appear to support the superiority of perioperative regional anesthesia–analgesia in improving patient outcomes,1–4 recent large-scale randomized controlled trials (RCTs)5 6 fail to show superiority. It is important to note, however, that the evidence examined over the past several years does not support the conclusion that regional anesthesia leads to worse outcomes for patients when compared with general anesthesia.7",
  "authors": [
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care Medicine and Pain Management, Hospital for Special Surgery, New York, New York, USA",
        "Department of Anesthesiology, Weill Cornell Medicine, New York, New York, USA"
      ],
      "name": "Christopher L Wu"
    },
    {
      "affiliations": [
        "Anesthesiology, University of Michigan Michigan Medicine, Ann Arbor, Michigan, USA"
      ],
      "name": "Mark C Bicket"
    },
    {
      "affiliations": [
        "Department of Anesthesiology, Critical Care Medicine and Pain Management, Hospital for Special Surgery, New York, New York, USA",
        "Department of Anesthesiology, Weill Cornell Medicine, New York, New York, USA"
      ],
      "name": "Stavros G Memtsoudis"
    }
  ],
  "title": "Does regional anesthesia lead to superior perioperative patient outcomes? Challenges and opportunities in study design",
  "uid": "d0f1024e-5abc-5a3c-a061-552c733b5291"
}