{
  "abstract": "A 37-year-old woman had a 3-week history of headache with brief intermittent episodes of confusion and collapse. There were no neurological signs. Serum IgG4 concentration was normal (0.24 g/L, normal 0.04–0.86) as were an electroencephalogram, cerebrospinal fluid analysis and whole body fluorodeoxyglucose positron emission tomography. MR scan of brain with venography showed parafalcine dural thickening with occlusion of the superior sagittal sinus (figure 1). Dural biopsy confirmed the diagnosis of IgG4-related pachymeningitis (figure 2) with secondary cerebral venous sinus thrombosis. Her symptoms resolved with levetiracetam, anticoagulation (warfarin) and prednisolone (40 mg orally one time per day, weaning to the maintenance of 5 mg one time per day). The patient did not wish to take a steroid-sparing agent. There has been no subsequent clinical or radiological evolution over 3 years.",
  "authors": [
    {
      "affiliations": [
        "Faculty of Health and Life Sciences, University of Bristol, Bristol, UK",
        "Department of Neurology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "Lu Yang"
    },
    {
      "affiliations": [
        "Faculty of Health and Life Sciences, University of Bristol, Bristol, UK",
        "Department of Neurology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "Stefania Kaninia"
    },
    {
      "affiliations": [
        "Department of Neuropathology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "Kathryn Urankar"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "William Brown"
    },
    {
      "affiliations": [
        "Department of Neurology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "Konrad Szewczyk-Krolikowski"
    },
    {
      "affiliations": [
        "Faculty of Health and Life Sciences, University of Bristol, Bristol, UK",
        "Department of Neurology, Southmead Hospital, North Bristol NHS Trust, Bristol, UK"
      ],
      "name": "Claire M Rice"
    }
  ],
  "title": "Cerebral venous sinus thrombosis complicating IgG4-related hypertrophic pachymeningitis",
  "uid": "14bd5c80-0fd3-58a8-b125-3c93b64a9a99"
}