{
  "abstract": "A 35-year-old woman developed visual impairment over 2 days following flu-like symptoms. On examination, she had binasal hemianopia, hyper-reflexia and patchy reduced pinprick sensation. Funduscopy was normal. Detailed visual field testing confirmed predominantly binasal field defects (figure 1A). MR scan of the brain showed T2-fluid-attenuated inversion recovery-hyperintense lesions involving the lateral geniculate nuclei and dorsolateral thalami (figure 2A), also involving the mammillary bodies and spinal cord. Nasopharyngeal swab identified influenza A virus. Serum testing for aquaporin-4-IgG and myelin oligodendrocyte glycoprotein-IgG was negative, and there were no cerebrospinal fluid-specific oligoclonal bands. Intriguingly, her sister had also developed visual impairment at age 15 following a flu-like illness, with similar predominantly binasal field defects (figure 1B) and subtle lateral geniculate nuclei lesions on brain imaging (figure 2B).",
  "authors": [
    {
      "affiliations": [
        "Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada"
      ],
      "name": "Jihad Al Kharbooshi"
    },
    {
      "affiliations": [
        "Department of Medical Imaging, University of Western Ontario, London, Ontario, Canada"
      ],
      "name": "Michael Mayich"
    },
    {
      "affiliations": [
        "Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada",
        "Department of Pathology and Laboratory Medicine, University of Western Ontario, London, Ontario, Canada"
      ],
      "name": "Adrian Budhram"
    },
    {
      "affiliations": [
        "Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada"
      ],
      "name": "Juan Racosta"
    }
  ],
  "title": "Binasal visual field defects in genetic acute necrotising encephalopathy",
  "uid": "9136c673-fe6c-5630-9138-216f5c849a6e"
}