{
  "abstract": "There are many possible causes for acute encephalitis, and systemic causes can be easily overlooked. We report a woman with initial status epilepticus, marked working memory impairment and ataxia, which developed 1 week following the ChAdOx1 SARS-CoV-2 (Astra-Zeneca) vaccination. Although lumbar puncture detected a paraprotein, it was not until she developed the hallmark cutaneous features of scleromyxoedema several months later that we recognised this as the dermato-neuro syndrome. Given the temporal association, the SARS-CoV-2 vaccination was a likely trigger, and the decision whether to give subsequent vaccinations during the heat of the COVID-19 pandemic added a layer of complexity to decision making. We review the literature regarding dermato-neuro syndrome in the setting of SARS-CoV-2 vaccination and explore its unique features.",
  "authors": [
    {
      "affiliations": [
        "Department of Neurology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"
      ],
      "name": "Bernard Liem"
    },
    {
      "affiliations": [
        "Dermatology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"
      ],
      "name": "Gorav Wali"
    },
    {
      "affiliations": [
        "Dermatology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"
      ],
      "name": "Sabrina Khan"
    },
    {
      "affiliations": [
        "Pathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK"
      ],
      "name": "Eleni Ieremia"
    },
    {
      "affiliations": [
        "Haematology, John Radcliffe Hospital, Oxford, UK"
      ],
      "name": "Karthik Ramasamy"
    },
    {
      "affiliations": [
        "Department of Neurology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK",
        "Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK"
      ],
      "name": "Alexander Thompson"
    },
    {
      "affiliations": [
        "Department of Neurology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK",
        "Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK"
      ],
      "name": "Arjune Sen"
    }
  ],
  "title": "Dermato-neuro syndrome triggered by SARS-CoV-2 vaccination",
  "uid": "7046bb88-8e15-5e37-a305-b49b115442cc"
}