{
  "abstract": "Antiphospholipid antibody syndrome (APS) may rarely present with isolated thrombocytopenia that may be diagnosed and treated as immune thrombocytopenic purpura. A 32-year-old woman was given eltrombopag (a thrombopoietin receptor agonist) to treat presumed immune thrombocytopenic purpura. She developed catastrophic APS, with multiple ischaemic infarcts, microvascular coronary thrombosis and digital gangrene. She improved after stopping eltrombopag and starting immunotherapy (corticosteroids, intravenous immunoglobulin and rituximab) but was left with significant neurological morbidity.",
  "authors": [
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Bhargav Chandan Sumanth T"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Aditya Vijayakrishnan Nair"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Angel Miraclin T"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "George Abraham Ninan"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Brunda K"
    },
    {
      "affiliations": [
        "Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Leena RV"
    },
    {
      "affiliations": [
        "Department of Radiology, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Harshad Arvind Vanjare"
    },
    {
      "affiliations": [
        "Department of Haematology, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Joshi Nutan Damodar"
    },
    {
      "affiliations": [
        "Department of Haematology, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Yamuna Naik"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Appaswamy Thirumal Prabhakar"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Ajith Sivadasan"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Vivek Mathew"
    },
    {
      "affiliations": [
        "Department of Neurological sciences, Christian Medical College, Vellore, Tamil Nadu, India"
      ],
      "name": "Sanjith Aaron"
    }
  ],
  "title": "Catastrophic antiphospholipid antibody syndrome provoked by eltrombopag",
  "uid": "f29dff99-88ff-5a25-b1d8-ce63c9e8e7b8"
}