{
  "abstract": "Background Intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT) are the standard of care for eligible acute ischemic stroke patients. Both therapies are time-sensitive and reliant on accurate clinical history in the acute setting. UC Irvine Medical Center is unique in that it cares for a diverse patient population with a relatively large Asian community. Here, we evaluated the association of acute stroke care benchmarks and hospital presentation delay with language barriers, race, and ethnicity.Methods We identified 439 patients who underwent either IVT or EVT at our institution between January 2019 and December 2024. Subjects were categorized based on their primary language, race, and ethnicity. Acute stroke care benchmarks: door-to-needle (DTN) and door-to-puncture times (DTP) were extracted. To quantify the delay in presenting to the hospital for stroke care, we calculated the time from the last known well to hospital arrival (LKWTA).Results Of the 439 subjects, 272 (62%) had English as their primary language, compared to 77 (18%) Spanish and 90 (20%) Other languages. A one-way analysis of variance was conducted. There was no statistically significant difference in the mean DTN (39.4, 41.6, and 36.9) or DTP (105.6, 96.8, and 105.3) between the three language groups. Similarly, no statistically significant difference was noted in the mean LKWTA (238, 271, and 311.5). There was, however, a trend toward delayed presentation for non-English-speaking patients.Regarding race, 128 (29%) identified as Asian, while 311 (71%) identified with other races or had no racial identification in our system. Independent-samples t-tests were conducted. A statistically significant difference was observed for LKWTA as Asian patients had a mean difference (delay) of 77.1 minutes compared to other (95% CI [4.06, 150.09]; p = 0.039). There was no statistically significant mean difference with DTN or DTP (-1 and +15.7). A similar analysis was conducted for ethnicity (Hispanic Vs. non-Hispanic), with no statistically significant results.Conclusion Neither primary language nor ethnicity was associated with differences in acute stroke care benchmarks or LKWTA times. There was a statistically significant correlation between Asian race and delayed presentation to the hospital.Disclosures F. Bounni: None. M. Carrillo: None. M. Shafie: None. W. Yu: None.Abstract E-297 Figure 1-2",
  "authors": [
    {
      "affiliations": [
        "Baptist Health South Florida, Miami, FL",
        "FIU Herbert Wertheim College of Medicine, Miami, FL"
      ],
      "name": "F Bounni"
    },
    {
      "affiliations": [
        "University of California Irvine Medical Center, Orange, CA"
      ],
      "name": "M Carrillo"
    },
    {
      "affiliations": [
        "University of California Irvine Medical Center, Orange, CA"
      ],
      "name": "M Shafie"
    },
    {
      "affiliations": [
        "University of California Irvine Medical Center, Orange, CA"
      ],
      "name": "W Yu"
    }
  ],
  "title": "E-297 Language, racial, and ethnic disparities in acute stroke therapy. a single-center review",
  "uid": "49dadad9-8325-5862-856e-06d5b08c2d34"
}