{
  "abstract": "Background/Objectives Manometry studies can be of great importance in neurointerventional practice, particularly in patients with Idiopathic Intracranial Hypertension (IIH) caused by Venous Sinus Stenosis (VSS), but often rely on catheter-based systems that are prone to inaccuracy. This study examines the impact of catheter size on venous sinus pressure gradient accuracy and evaluates the validity of these measurements compared with a no-catheter reference standard in a simulation model.Methods A Finite Element Method (FEM)-based model was developed using COMSOL Multiphysics 6.2 to simulate venous pressure measurements. The model included varying degrees of stenosis (20%, 40%, 60%, 80%) and catheter diameters (0.014-0.038 inches). The Fluid-Structure Interaction (FSI) method was used to account for dynamic interactions between blood flow, the vessel wall, stenosis and catheters. Pressure gradients were calculated by comparing prestenotic pressure (100 mmHg) with poststenotic pressure, and the results were normalised to a gold standard (no catheter).Results Catheter size significantly influenced pressure gradient measurements, with larger catheters causing greater distortions. For vessels with 20% stenosis, the distortion factor increased from 1.65 (0.014 inch catheter) to 2.85 (0.038 inch catheter). This trend was less pronounced in vessels with greater degrees of stenosis, with the factor increasing from 1.10 to 1.13 in 80% stenosed vessels. These findings suggest that catheter-induced distortions are more pronounced in mild stenosis, while the stenosis itself becomes the dominant factor with greater severity.Conclusions Catheter diameter and stenosis severity have important impacts on the accuracy of venous sinus pressure measurements. These results underscore the need for the investigation of alternative technologies, such as pressure wire guidewires, that may impact guidelines for VSS intervention.Disclosures H. Al-Fiadh: None.",
  "authors": [
    {
      "affiliations": [
        "Austin Health, Heidelberg, Australia"
      ],
      "name": "H Al-Fiadh"
    }
  ],
  "title": "O-058 Navigating errors in cerebral catheter-based pressure measurements: can we take the pressure?",
  "uid": "32cd3d15-af2f-58b5-893c-2cb97e9cdf7f"
}