{
  "abstract": "Background Socioeconomic status influences health outcomes, including cerebrovascular diseases. Patients from socioeconomically deprived areas may present with more severe conditions due to delayed access to care. This study evaluates the association between neighborhood-level deprivation, measured by the Area Deprivation Index (ADI), and the treatment of ruptured intracranial aneurysms (RIAs) compared with unruptured intracranial aneurysms (UIAs) across multiple centers.Methods This retrospective cohort study analyzed data from 4517 patients treated for cerebral aneurysms at 10 US comprehensive stroke centers between 2018 and 2024. Patients were stratified by national ADI decile based on their residential addresses. Multivariable logistic regression was used to examine the relationship between ADI and aneurysm rupture (reference being unruptured aneurysms) and controlled for age, sex, smoking history, family history, and race.Results Of 4517 total patients, 1260 (27.9%) underwent treatment of RIAs. Multivariable analysis confirmed ADI as an independent predictor of presentation for treatment of RIA (odds ratio (OR)=1.100, 95% confidence interval (CI)=1.068–1.133, P<0.0001) after adjusting for age, sex, smoking history, and race. This corresponds to a 10% increase in likelihood of presenting for treatment of a ruptured vs unruptured intracranial aneurysm with each ADI decile.Conclusion Socioeconomic deprivation independently predicts treatment of RIAs compared with the treatment of UIAs. These findings highlight disparities in aneurysm detection and management, emphasizing the need for targeted preventive care and accessible screening programs to mitigate the impact of socioeconomic disadvantage on cerebral aneurysm outcomes.",
  "authors": [
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "Samhita Bheemireddy"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "Avi A Gajjar"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "Mofetoluwa Abe"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "Amanda Custozzo"
    },
    {
      "affiliations": [
        "Neurosurgery, Mayfield Brain & Spine, Cincinnati, Ohio, USA"
      ],
      "name": "Sonia Lipp"
    },
    {
      "affiliations": [
        "Neurosurgery, Mayfield Brain & Spine, Cincinnati, Ohio, USA"
      ],
      "name": "Andrew Ringer"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Montefiore Medical Center, Bronx, New York, USA"
      ],
      "name": "Muhammed Amir Essibayi"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Montefiore Medical Center, Bronx, New York, USA"
      ],
      "name": "David Altschul"
    },
    {
      "affiliations": [
        "Neurosurgery, Geisinger Health, Danville, Pennsylvania, USA"
      ],
      "name": "Oded Goren"
    },
    {
      "affiliations": [
        "Neurosurgery, Geisinger Health, Danville, Pennsylvania, USA"
      ],
      "name": "Jeffrey Oliver"
    },
    {
      "affiliations": [
        "Neurosurgery, Henry Ford Health System, Detroit, Michigan, USA"
      ],
      "name": "Jared C Reese"
    },
    {
      "affiliations": [
        "Neurosurgery, Henry Ford Health System, Detroit, Michigan, USA"
      ],
      "name": "Pouya Entezami"
    },
    {
      "affiliations": [
        "Neurosurgery, Prisma Health Upstate, Greenville, South Carolina, USA"
      ],
      "name": "Imran Chaudry"
    },
    {
      "affiliations": [
        "Neurosurgery, Prisma Health Upstate, Greenville, South Carolina, USA"
      ],
      "name": "Shawn Manos"
    },
    {
      "affiliations": [
        "Neurosurgery, Prisma Health Upstate, Greenville, South Carolina, USA"
      ],
      "name": "Aquilla Scott Turk IV"
    },
    {
      "affiliations": [
        "Department of Neurology, University of Iowa Health Care, Iowa City, Iowa, USA"
      ],
      "name": "Elena Sagues"
    },
    {
      "affiliations": [
        "Department of Neurology, University of Iowa Health Care, Iowa City, Iowa, USA"
      ],
      "name": "Andres Gudino"
    },
    {
      "affiliations": [
        "Department of Neurology, University of Iowa Health Care, Iowa City, Iowa, USA"
      ],
      "name": "Edgar A Samaniego"
    },
    {
      "affiliations": [
        "Division of Neurointerventional Radiology, University of Massachusetts System, Boston, Massachusetts, USA"
      ],
      "name": "Anna Luisa Kühn"
    },
    {
      "affiliations": [
        "Division of Neurointerventional Radiology, University of Massachusetts System, Boston, Massachusetts, USA"
      ],
      "name": "Jasmeet Singh"
    },
    {
      "affiliations": [
        "Division of Neurointerventional Radiology, University of Massachusetts System, Boston, Massachusetts, USA"
      ],
      "name": "Ajit S Puri"
    },
    {
      "affiliations": [
        "Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA"
      ],
      "name": "Joanna Mary Roy"
    },
    {
      "affiliations": [
        "Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA"
      ],
      "name": "Kareem ElNaamani"
    },
    {
      "affiliations": [
        "Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA"
      ],
      "name": "M. Reid Gooch"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, University at Buffalo, Buffalo, New York, USA"
      ],
      "name": "Vinay Jaikumar"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, University at Buffalo, Buffalo, New York, USA"
      ],
      "name": "Adnan H Siddiqui"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "Alan S Boulos"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "John C Dalfino"
    },
    {
      "affiliations": [
        "Department of Neurosurgery, Albany Medical Center, Albany, New York, USA"
      ],
      "name": "Alexandra R Paul"
    }
  ],
  "title": "Multicenter study of association between socioeconomic status and treatment of ruptured cerebral aneurysms compared to unruptured cerebral aneurysms: insights from 4,517 patients using the area deprivation index",
  "uid": "7c21ecf7-a391-5e0c-afff-f8c4ff9b16fc"
}