{
  "abstract": "Background The increasing availability of neuroimaging tests has led to a rise in the identification of incidental unruptured intracranial aneurysms (UIAs). Their management is under debate, with no consensus on their follow-up strategy, which can cause anxiety in patients. Our aim is to evaluate the impact of diagnosis and imaging follow-up on daily activities and quality of life.Methods A multicenter cross-sectional study was carried out in patients with UIAs undergoing watchful waiting. Exclusion criteria were history of stroke, renal polycystic disease, symptomatic aneurysms, intervention or scheduled for intervention. The patients completed an anonymous 36-question survey about their habits and perceived quality of life after diagnosis through a validated questionnaire (PROMIS).Results We obtained 73 responses from 183 patients identified in eight hospitals (40%), 68 of which were included in the study (50 women (74%), median (IQR) age 62 (55–70) years). Forty-nine patients (72%) underwent at least one imaging follow-up per year. Forty-two patients (63%) found follow-up tests reassuring and 12 (18%) experienced concern about the results. Nineteen patients (28%) reported adopting a healthier lifestyle since diagnosis, while 13 (19%) acknowledged a negative impact on their daily activities. Forty-six (68%) admitted avoiding or conditioning at least one activity or situation from a list. PROMIS scores were similar to those of the general reference population. Overall, 77% rated their quality of life as ‘good’ or better.Conclusions The diagnosis of UIAs seems to influence the activities of the majority of patients. However, follow-up yielded more benefit in the form of healthier lifestyles than harm to daily activities, without detriment to their perceived quality of life.",
  "authors": [
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Jorge Rodríguez-Pardo"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Jesús García-Castro"
    },
    {
      "affiliations": [
        "Department of Neurology, San Carlos University Hospital Clinic, Complutense University of Madrid, IdiSSC, Madrid, Spain"
      ],
      "name": "Carlos Gómez-Escalonilla"
    },
    {
      "affiliations": [
        "Department of Neurology, Fundación Jiménez Diaz University Hospital, Universidad Autónoma de Madrid, Madrid, Spain"
      ],
      "name": "Araceli García-Torres"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain"
      ],
      "name": "Andrés García-Pastor"
    },
    {
      "affiliations": [
        "Department of Neurology, La Princesa University Hospital, IIS-IP, Universidad Autónoma de Madrid, Madrid, Spain"
      ],
      "name": "José Vivancos-Mora"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital Universitario Rey Juan Carlos, Mostoles, Spain"
      ],
      "name": "José Fernández-Ferro"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Universidad de Alcalá, Madrid, Spain"
      ],
      "name": "Antonio Cruz-Culebras"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital Universitario Puerta de Hierro, Universidad Autónoma de Madrid, Madrid, Spain"
      ],
      "name": "Joaquín Carneado-Ruiz"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Juan Granja-López"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Carlos Estebas-Armas"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Manuel Lorenzo-Diéguez"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Ricardo González-Sarmiento"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Raúl García-Yu"
    },
    {
      "affiliations": [
        "Department of Radiology, IdiPAZ Health Research Institute, Madrid, Spain"
      ],
      "name": "Alberto Alvarez-Muelas"
    },
    {
      "affiliations": [
        "Department of Neurology, Fundación Jiménez Diaz University Hospital, Universidad Autónoma de Madrid, Madrid, Spain"
      ],
      "name": "Inmaculada Navas-Vinagre"
    },
    {
      "affiliations": [
        "Department of Neurology, Fundación Jiménez Diaz University Hospital, Universidad Autónoma de Madrid, Madrid, Spain"
      ],
      "name": "Marta Oses-Lara"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital General Universitario Gregorio Marañón, Madrid, Spain"
      ],
      "name": "Ana Iglesias-Mohedano"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital Universitario Rey Juan Carlos, Mostoles, Spain"
      ],
      "name": "Laura Santos"
    },
    {
      "affiliations": [
        "Department of Radiology, Hospital Universitario Puerta de Hierro, Universidad Autónoma de Madrid, Madrid, Spain"
      ],
      "name": "Carmen de la Rosa"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "María Alonso de Leciñana"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Exuperio Díez-Tejedor"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Gerardo Ruiz-Ares"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Ricardo Rigual"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Elena de Celis"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Carlos Hervás-Testal"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Laura Casado-Fernández"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Laura González-Martín"
    },
    {
      "affiliations": [
        "Department of Radiology, IdiPAZ Health Research Institute, Madrid, Spain"
      ],
      "name": "Pedro Navía"
    },
    {
      "affiliations": [
        "Department of Radiology, IdiPAZ Health Research Institute, Madrid, Spain"
      ],
      "name": "Andres Fernandez-Prieto"
    },
    {
      "affiliations": [
        "Department of Radiology, IdiPAZ Health Research Institute, Madrid, Spain"
      ],
      "name": "Remedios Frutos"
    },
    {
      "affiliations": [
        "Department of Neurology, Hospital La Paz Institute for Health Research-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain"
      ],
      "name": "Blanca Fuentes"
    }
  ],
  "title": "Burden of incidental cerebral aneurysms on lifestyle and quality of life: a survey of patients in expectant management (the SPICE Study)",
  "uid": "9e04dfb8-cb17-528a-9e48-cea214985f27"
}