{
  "abstract": "Background Efficient recanalization of occluded cerebral arteries is crucial in the treatment of acute ischemic stroke. Double stent retrievers have shown the potential to enhance the rates of recanalization on the first pass. This study aims to evaluate the efficacy and safety of the double stent retriever technique and the predictors of achieving first-pass effect in patients with acute ischemic stroke.Methods This prospective multicenter study involved 209 patients from 16 comprehensive stroke centers in Spain. Patients with occlusions in the anterior circulation were treated using the Aperio Hybrid double stent retriever. The study examined various deployment techniques, including simultaneous and sequential deployment and stent configurations, comparing the Y-shaped and parallel configurations.Results The double stent retriever technique achieved a first-pass effect in 72.7% of cases and a final successful recanalization rate of 99.5%. The Y-shaped configuration was significantly associated with higher recanalization rates on the first pass (OR 2.59, 95% CI 1.18 to 5.68, P=0.02). Procedural complications were mild to moderate in 6.7% and severe in 1.5% of cases, with symptomatic intracranial hemorrhage occurring in 3.3% of patients. At 3 months follow-up, 57.2% of patients achieved a good clinical outcome, with a mortality rate of 15.1%.Conclusion The findings support the efficacy of the double stent retriever technique, particularly the Y-shaped configuration, in achieving high recanalization rates on the first pass with an acceptable safety profile. This technique may offer clinical benefits for future acute ischemic stroke treatment protocols.",
  "authors": [
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Clinico San Carlos, Madrid, Spain"
      ],
      "name": "Carlos Pérez-García"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Salamanca, Salamanca, Spain"
      ],
      "name": "Miguel Castaño"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Salamanca, Salamanca, Spain"
      ],
      "name": "Juan Carlos Llibre"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Salamanca, Salamanca, Spain"
      ],
      "name": "Luis Vargas"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Clinico San Carlos, Madrid, Spain"
      ],
      "name": "Alfonso López-Frías"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Clinico San Carlos, Madrid, Spain"
      ],
      "name": "Santiago Rosati"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Burgos, Burgos, Spain"
      ],
      "name": "Jose Luis López"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Burgos, Burgos, Spain"
      ],
      "name": "Jesus Venegas"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario Cruces, Barakaldo, Spain"
      ],
      "name": "Eva González"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario Cruces, Barakaldo, Spain"
      ],
      "name": "Jon Fondevila"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Spain"
      ],
      "name": "Mariano Espinosa de Rueda"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Spain"
      ],
      "name": "Joaquín Zamarro"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Complejo Asistencial Universitario de Leon, Leon, Spain"
      ],
      "name": "Sebastián Baldi"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Regional Universitario de Malaga, Malaga, Spain"
      ],
      "name": "Teresa Díaz"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain"
      ],
      "name": "Carmen de la Rosa"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Complejo Hospitalario de Cáceres, Caceres, Spain"
      ],
      "name": "Juan Chaviano Grajera"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario 12 de Octubre, Madrid, Spain"
      ],
      "name": "Federico Ballenilla Marco"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Spain"
      ],
      "name": "Victor Cuba"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario de Getafe, Getafe, Spain"
      ],
      "name": "José M Muñoz Olmedo"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario Ramon y Cajal, Madrid, Spain"
      ],
      "name": "Jose Carlos Mendez"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain"
      ],
      "name": "Sebastian Remollo"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital de Navarra, Pamplona, Spain"
      ],
      "name": "Rebeca Bermejo"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Universitario Basurto, Bilbao, Spain"
      ],
      "name": "Edison Morales"
    },
    {
      "affiliations": [
        "Neurology, Hospital Clínico San Carlos, Madrid, Spain"
      ],
      "name": "Carlos Gómez-Escalonilla"
    },
    {
      "affiliations": [
        "Interventional Neuroradiology, Hospital Clinico San Carlos, Madrid, Spain"
      ],
      "name": "Manuel Moreu"
    }
  ],
  "title": "Impact of double stent retriever configuration on first-pass effect in stroke: a multicenter study",
  "uid": "5e804574-1b5c-55d8-9a31-c6e9ca43cdb3"
}