{
  "abstract": "Objectives To evaluate the technical feasibility, safety, and short-term to mid-term efficacy of the antithrombogenic-coated CARESTO stent in the endovascular treatment of acute symptomatic cervical internal carotid artery dissections (CICAD) with hemodynamically relevant stenosis and disabling neurological deficits.Methods This retrospective multicenter study evaluated patients with acute symptomatic CICAD who underwent endovascular treatment with the CARESTO stent. Clinical endpoints included changes in the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS) scores. Imaging endpoints assessed vessel patency, arterial diameter improvement, and revascularization success, defined as a modified Thrombolysis in Cerebral Infarction (mTICI) score ≥2b. Safety was evaluated by documenting periprocedural complications.Results Between January 2023 and May 2025, 31 patients were treated across six participating neurovascular centers. The mean age was 52.3±10.2 years; 54.8% were female. Stent deployment was successful in all cases. In those with intracranial vessel occlusion (n=22), recanalization was achieved in all patients (mTICI 3: 61.3%; mTICI 2c: 22.6%; mTICI 2b: 16.1%). ICA diameter improved from 1.0±0.5 mm to 4.6±0.6 mm. Median NIHSS score decreased from 11 (IQR 8–14.5) to 1 (IQR 1–3) at 3 months; mRS≤2 was achieved in 83.9%. All stents remained patent, with no major complications or deaths.Conclusion This initial multicenter experience suggests that the CARESTO stent is technically feasible and may offer a safe and effective treatment option for acute CICAD. These findings support further prospective evaluation in larger cohorts.",
  "authors": [
    {
      "affiliations": [
        "Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany",
        "Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Mohammad Almohammad"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, University Hospital Basel, Basel, Switzerland",
        "Department of Radiology and Neuroradiology, Stadtspital Zürich Triemli, Zürich, Switzerland"
      ],
      "name": "Peter B Sporns"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, HELIOS Medical Center, Campus of MSH Medical School Hamburg, Schwerin, Germany"
      ],
      "name": "Gabriel Broocks"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Charité - Universitätsmedizin Berlin, Berlin, Germany"
      ],
      "name": "Mike Peter Wattjes"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Klinikum Stuttgart Katharinenhospital, Stuttgart, Germany"
      ],
      "name": "Ali khanafer"
    },
    {
      "affiliations": [
        "Department of Radiology, St Vincenz Hospital Paderborn, Paderborn, Germany"
      ],
      "name": "Mete Dadak"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany",
        "Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Bayan Alhaj Moustafa"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany",
        "Department of Radiology and Neuroradiology, Rhön Klinikum Campus Bad Neustadt, Bad Neustadt an der Saale, Germany"
      ],
      "name": "Tawfik Moher Alsady"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany",
        "Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Abdallah Aburub"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany",
        "Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Lisa Hekers"
    },
    {
      "affiliations": [
        "Department of Neurology, Philipps-University Marburg, Marburg, Germany",
        "Department of Neurology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Lars Timmermann"
    },
    {
      "affiliations": [
        "Department of Neurology, Philipps-University Marburg, Marburg, Germany",
        "Department of Neurology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Anja Gerstner"
    },
    {
      "affiliations": [
        "Department of Neurology, Philipps-University Marburg, Marburg, Germany",
        "Department of Neurology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany"
      ],
      "name": "Ole Simon"
    },
    {
      "affiliations": [
        "Department of Diagnostic and Interventional Radiology and Neuroradiology, Schön Klinik Neurstadt, Neustadt in Holstein, Germany"
      ],
      "name": "Thomas Eckey"
    },
    {
      "affiliations": [
        "Department of Neuroradiology, Philipps-Universitat Marburg, Marburg, Germany",
        "Department of Neuroradiology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany",
        "Department of Radiology and Neuroradiology, Rhön Klinikum Campus Bad Neustadt, Bad Neustadt an der Saale, Germany"
      ],
      "name": "André Kemmling"
    }
  ],
  "title": "Initial experience with the antithrombogenic-coated CARESTO stent for acute symptomatic cervical internal carotid artery dissections: multicenter study",
  "uid": "3c0bbca9-f396-571f-bfac-68bf25693818"
}