{
  "abstract": "Introduction The MDRinAIS study is an EU-funded initiative that aims to develop a telemedicine-enabled management pathway for patients with acute ischemic stroke (AIS) due to large vessel occlusion.Aim of Study To reduce treatment delays and improve AIS patient outcomes.Method This retrospective multicentric study included AIS patients treated with the ‘drip and ship’ model between January 2018 and December 2021 at three centers: Italy, Switzerland, and Spain. Patients were categorized by treatment type (mechanic trombectomy, fibrinolysis, or both) and modified Rankin Scale (mRS). Timing metrics (in minutes) included admission-to-groin puncture (DTG), admission-to-fibrinolysis initiation (DTIF), fibrinolysis-to-hub arrival (DoF), and admission-to-hub groin puncture (DT).Results 572 patients were enrolled (Spain: 22.38%; Italy: 37.41%; Switzerland: 40.21%). Significant differences in treatment distribution, times and complications were observed across centers (p<0.001). Italy’s (67.70±42.02) and Switzerland’s (55.97±104.5) DTG time was significantly lower than Spain’s (96.92±44.96; p=0.0031 and p<0.001, respectively). Similar differences were noted for DT, DTIF and DoF times. Post-treatment complications included: vessel dissection (Italy: 0.9%, Spain: 13.68%, Switzerland: 5.13%, p<0.001); embolism in new territories (Spain: 8.42%, Switzerland: 4.08%, p<0.001); and other complications (Italy: 3.3%, Spain: 24.21%, Switzerland: 14.35%, p<0.001); distalization rates showed no differences. We also found differences between pre and post-stroke mRS among the centers (p<0.001).Abstract A286 Figure 1Conclusion These findings reveal critical variability in treatment options, complications and times, underscoring the need for standardized protocols and telemedicine coordination to improve AIS management and outcomes.Conflict of Interest No",
  "authors": [
    {
      "affiliations": [
        "San Donato Hospital, Arezzo, Italy"
      ],
      "name": "Irene Grazzini"
    },
    {
      "affiliations": [
        "Misericordia Hospital, Grosseto, Italy"
      ],
      "name": "Davide Del Roscio"
    },
    {
      "affiliations": [
        "Misericordia Hospital, Grosseto, Italy"
      ],
      "name": "Marco Cirinei"
    },
    {
      "affiliations": [
        "AOUS, Siena, Italy"
      ],
      "name": "Sofia Lo Conte"
    },
    {
      "affiliations": [
        "AOUS, Siena, Italy"
      ],
      "name": "Matteo Zanoni"
    },
    {
      "affiliations": [
        "AOUS, Siena, Italy"
      ],
      "name": "Martin Vitiello"
    },
    {
      "affiliations": [
        "AOUS, Siena, Italy"
      ],
      "name": "Alessandra Cartocci"
    },
    {
      "affiliations": [
        "Hospital Universitario Virgen de la Victoria IBIMA, malaga, Spain"
      ],
      "name": "Carlos De la Cruz Cosme"
    },
    {
      "affiliations": [
        "Hospital Universitario Virgen de la Victoria IBIMA, malaga, Spain"
      ],
      "name": "Agustin Rodrigruez Belli"
    },
    {
      "affiliations": [
        "Centre hospitalier universitaire vaudois, Lusanne, Switzerland"
      ],
      "name": "Richard Mospan"
    },
    {
      "affiliations": [
        "Centre hospitalier universitaire vaudois, Lusanne, Switzerland"
      ],
      "name": "Francesco Puccinelli"
    },
    {
      "affiliations": [
        "SYNYO, Vienna, Austria"
      ],
      "name": "Alexander Nikolov"
    },
    {
      "affiliations": [
        "Riga Stradins University, Department of Rehabilitation, Riga, Latvia"
      ],
      "name": "Guna Semjonova"
    },
    {
      "affiliations": [
        "AOUS, Siena, Italy"
      ],
      "name": "Sandra Bracco"
    },
    {
      "affiliations": [
        "AOUS, Siena, Italy"
      ],
      "name": "Susanna Guerrini"
    }
  ],
  "title": "A286 Optimizing acute ischemic stroke management with drip and ship model in europe: preliminary results from the MDRinAIS Study (THCS, JTC 2023)",
  "uid": "f8671468-35b2-5b65-8c40-f5565d12c90c"
}