{
  "abstract": "Introduction Interstitial Lung Disease (ILD) is a common extra-articular manifestation of rheumatoid arthritis (RA) that substantially contributes to both morbidity and mortality rates. Prior detection of pulmonary involvement is highly beneficial in asymptomatic patients. Therefore, the present study was conducted to determine the prevalence of Interstitial Lung Disease by pulmonary function test & diffusing capacity of the lung for carbon monoxide in patients of rheumatoid arthritis who are clinically asymptomatic for Interstitial Lung Disease.Material and Methods The study was undertaken in General medicine department, MMIMSR, Mullana, Haryana India. A total of 50 patients above the age of 18 years diagnosed with Rheumatoid Arthritis (classified as per ACR/EULAR 2010 criteria) were taken. Old & new case of pulmonary TB, bronchiectasis etc. were excluded. Chosen patients underwent thorough evaluation & disease severity was calculated. The respiratory system examination was conducted. After assessing clinically, biochemically & Chest X-ray, the patients were subjected to lung function test.Results In our study, 44 patients, (88%) were females & 6 (12%) were males with a mean age of 47.34 years. The mean disease duration was 7.18 years. 48 (96 %) subjects had high disease activity while 2 (4%) had moderate disease activity ( table 1). Prevalence of restrictive lung disease as per PFT was 62% while as per DLCO it was 58%. DLCO had sensitivity of 60.44%, specificity of 71.34% & accuracy of 72% while PFT had sensitivity of 69.47%, specificity of 62.57% & accuracy of 56% (figure 1). Hamish J. Farquhar et al. (1) also observed that mean age was 58.47 years with prevalence as per DLCO was 58%. This study offers a more in-depth analysis of lung function (FVC, FEV1) and emphasizes radiological progression and long term outcomes of RA-ILD as comparison to our study which focus on PFT and DLCO as early screening tools.Conclusions We observed that prevalence of ILD in patients of RA who are asymptomatic for ILD is high so PFT can be used as early screening tool being more sensitive & cost effective while DLCO being more specific & accurate can be used in patients unable to perform PFT.Abstract P.401 Figure 1Sensitivity and specificity of DLCO and PFTAbstract P.401 Table 1Demographic profile of patients",
  "authors": [
    {
      "affiliations": [
        "Maharishi Markhandeshwar University, Mullana, Ambala, India"
      ],
      "name": "Harmanjeet Singh Dhillon"
    }
  ],
  "title": "P.401 The prevalence of interstitial lung disease in diagnosed cases of rheumatoid arthritis in tertiary care center",
  "uid": "4e8dcac9-5921-5126-987f-9b843f02cec2"
}