{
  "abstract": "We present a case of anti-myelin-associated glycoprotein (anti-MAG) neuropathy in a 62-year-old male with sensory symptoms predominantly affecting the lower limbs. The patient reported a 10-month history of bilateral pins and needles sensation, initially in the toes and progressively extending to the ankles. Intermittent sensory disturbance was also noted in the hands, without weakness, imbalance, or autonomic dysfunction. His medical history included hypertension and hyperlipidemia, managed with statin therapy.Neurological examination found absent reflexes bilaterally, reduced vibration sense at the right ankle and left knee, and hypersensitivity to pinprick up to the ankles. No cerebellar signs were identified. Romberg’s test was negative. Laboratory findings showed positive anti-MAG antibodies and an IgM kappa paraprotein band on serum electrophoresis, with negative urine Bence Jones proteins. Electrophysiology demonstrated asymmetric, non-length-dependent neuropathy, despite the symmetrical clinical presentation. Following a multidisciplinary discussion, immunotherapy such as rituximab was deferred, and a haematology referral was made due to investigate the paraprotein.This case underscores the importance of considering anti-MAG neuropathy in patients presenting with sensory symptoms and no tremor, especially if the neurophysiological findings are in keeping with an inflammatory neuropathy.jidhin.raj@nhs.net",
  "authors": [
    {
      "affiliations": [
        "The Walton NHS Foundation Trust"
      ],
      "name": "Raj Jidhin"
    },
    {
      "affiliations": [
        "The Walton NHS Foundation Trust"
      ],
      "name": "Davies Rhys"
    }
  ],
  "title": "7 Common symptoms, uncommon neuropathy: a case of anti-MAG neuropathy",
  "uid": "8295b35a-58f6-53d4-8ec7-3e70e8acb539"
}