{
  "abstract": "As part of the special Journal for ImmunoTherapy of Cancer (JITC) series, “Myeloid Cells in Immuno-Oncology,” leading experts were asked to provide their perspectives and answer provocative questions on controversial and evolving areas in the field of myeloid biology. Their responses below aim to further the discussion and help advance the biological understanding of myeloid cell biology within the tumor and strategies to modulate the function and activity of myeloid cells for anticancer therapy.",
  "authors": [
    {
      "affiliations": [
        "Surgery, Brigham and Women’s Hospital, Boston, Massachusetts, USA",
        "Harvard Medical School, Boston, Massachusetts, USA"
      ],
      "name": "Jennifer L Guerriero"
    },
    {
      "affiliations": [
        "Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA"
      ],
      "name": "Miriam Merad"
    },
    {
      "affiliations": [
        "Université Paris-Saclay, Gustave Roussy, U1356 Next Generation Immuno-Oncology Research, Villejuif, France"
      ],
      "name": "Florent Ginhoux"
    },
    {
      "affiliations": [
        "Vita-Salute San Raffaele University, Milan, Italy",
        "San Raffaele-Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy"
      ],
      "name": "Renato Ostuni"
    },
    {
      "affiliations": [
        "Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands",
        "Oncode Institute, Utrecht, The Netherlands",
        "Department of Immunology, Leiden University Medical Center, Leiden, The Netherlands"
      ],
      "name": "Karin E de Visser"
    },
    {
      "affiliations": [
        "Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland",
        "AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland",
        "Ludwig Institute for Cancer Research, Lausanne, Switzerland",
        "Department of Oncology, Geneva University Hospitals, Geneva, Switzerland"
      ],
      "name": "Mikael J Pittet"
    },
    {
      "affiliations": [
        "Department of Otorhinolaryngology, Experimental and Translational Research Division, University Medicine Essen, Essen, Germany",
        "German Cancer Consortium, West German Cancer Center, Essen, Germany"
      ],
      "name": "Sven Brandau"
    },
    {
      "affiliations": [
        "Parker Institute for Cancer Immunotherapy and Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, New York, USA",
        "Department of Pharmacology, Swim Across America and Ludwig Collaborative Laboratory, Weill Cornell Medicine, New York, New York, USA"
      ],
      "name": "Taha Merghoub"
    },
    {
      "affiliations": [
        "Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA"
      ],
      "name": "Mikala Egeblad"
    },
    {
      "affiliations": [
        "Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg, Germany",
        "Department of Dermatology Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Baden-Württemberg, Germany",
        "DKFZ Hector Cancer Institute, University Medical Center Mannheim, Mannheim, Germany"
      ],
      "name": "Viktor Umansky"
    },
    {
      "affiliations": [
        "Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA"
      ],
      "name": "Lilian van Vlerken-Ysla"
    },
    {
      "affiliations": [
        "Tisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA"
      ],
      "name": "Thomas U Marron"
    },
    {
      "affiliations": [
        "Department of Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, Oregon, USA"
      ],
      "name": "Lisa M Coussens"
    },
    {
      "affiliations": [
        "Department of Oncology, Johns Hopkins University School of Medicine and The Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA",
        "Bloomberg∼Kimmel Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"
      ],
      "name": "Jelani C Zarif"
    },
    {
      "affiliations": [
        "Department of Immunology and Department of Breast Oncology, H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA"
      ],
      "name": "Brian Ruffell"
    },
    {
      "affiliations": [
        "OTD Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK"
      ],
      "name": "Simon T Barry"
    },
    {
      "affiliations": [
        "Department of Pathology, University of California, San Diego, San Diego, California, USA"
      ],
      "name": "Judith A Varner"
    },
    {
      "affiliations": [
        "ICC, Early Oncology, AstraZeneca, Gaithersburg, Maryland, USA"
      ],
      "name": "Dmitry I Gabrilovich"
    }
  ],
  "title": "Expert opinion on burning questions in cancer myeloid cell biology",
  "uid": "02bce6d3-9e5a-5832-b8d2-6f4ed3d0c350"
}
