{
  "abstract": "We read with great interest the recent publication by Yu et al, titled “Hypoxia upregulates the expression of PD-L1 via NPM1 in breast cancer”.1 The authors provide compelling evidence that hypoxic signaling activates the p-AKT pathway through HIF-1α, leading to increased expression of nucleophosmin 1 (NPM1), which subsequently upregulates PD-L1 and promotes immune evasion in breast cancer.",
  "authors": [
    {
      "affiliations": [
        "Anatomical Pathology, Singapore General Hospital, Singapore"
      ],
      "name": "Jabed Iqbal"
    }
  ],
  "title": "Letter to the editor: LSD1 as an upstream epigenetic regulator of NPM1-PD-L1 axis in hypoxia-driven immune evasion in breast cancer",
  "uid": "17501ced-84de-5664-8dbe-60492af02fef"
}