{
  "abstract": "Background Non-communicable diseases (NCDs) represent a significant cause of morbidity and mortality globally. Despite a strong evidence base outlining increased risk of communicable diseases and poor mental health in people who have experienced imprisonment, the risk of NCDs has not been quantified in previous reviews. This study aimed to describe the incidence of morbidity and mortality of physical NCDs in people who have experienced imprisonment compared with the general population in high-income countries.Methods We searched MEDLINE, Embase, CINAHL and SocINDEX (PROSPERO CRD42024540173) for comparative studies of morbidity or mortality from NCDs. Articles were assessed against predefined criteria to select studies that included people with experience of imprisonment; measured NCD incidence; compared incidence to a general population; and were conducted in a high-income country. Two reviewers conducted independent risk of bias assessment using an adapted version of the Newcastle-Ottawa Scale. Data were synthesised using random-effects meta-analyses and vote counting based on effect direction. Meta-regression and subgroup analysis investigated heterogeneity.Results Of 3085 articles screened, 32 were included providing 341 datapoints. Meta-analysis showed a higher risk of mortality from several diseases, including respiratory disease (risk ratio (RR) 2.38 (95% CI 1.18 to 4.80), I 2=97%), cardiovascular disease (RR 1.80 (95% CI 1.32 to 2.46), I2=99%), liver disease and cirrhosis (RR 2.50 (95% CI 1.08 to 5.77), I2=99%), digestive disease (RR 2.92 (95% CI 1.09 to 7.78), I2=99%), neurological disease (RR 1.94 (95% CI 1.09 to 3.44), I2=92%), head and neck cancer (RR 21.31 (95% CI 4.32 to 105.14), I2=97%), liver cancer (RR 4.07 (95% CI 2.34 to 7.08), I2=94%), cervical cancer (RR 3.95 (95% CI 3.11 to 5.01), I2=0%) and lung cancer (RR 1.95 (95% CI 1.34 to 2.85), I2=0%). Synthesis without meta-analysis also indicated imprisonment was associated with increased morbidity from multiple NCDs.Conclusions Several NCDs, including multiple cancers, cardiovascular disease, respiratory disease and liver disease, are substantially more common in people who have experienced imprisonment compared with the general population, highlighting a need for primary prevention and NCD management.",
  "authors": [
    {
      "affiliations": [
        "University of Glasgow School of Health and Wellbeing, Glasgow, UK"
      ],
      "name": "Beth Dorrans"
    },
    {
      "affiliations": [
        "University of Glasgow School of Health and Wellbeing, Glasgow, UK"
      ],
      "name": "Martha Tindall"
    },
    {
      "affiliations": [
        "University of Glasgow School of Health and Wellbeing, Glasgow, UK"
      ],
      "name": "Rachel M Thomson"
    },
    {
      "affiliations": [
        "Department of General Practice and Primary Care, University of Glasgow, Glasgow, UK"
      ],
      "name": "Shona Mackinnon"
    },
    {
      "affiliations": [
        "University of Glasgow School of Health and Wellbeing, Glasgow, UK"
      ],
      "name": "Philip Broadbent"
    },
    {
      "affiliations": [
        "University of Glasgow School of Health and Wellbeing, Glasgow, UK"
      ],
      "name": "Valerie Wells"
    },
    {
      "affiliations": [
        "Department of General Practice and Primary Care, University of Glasgow, Glasgow, UK"
      ],
      "name": "Andrea Elizabeth Williamson"
    },
    {
      "affiliations": [
        "University of Glasgow School of Health and Wellbeing, Glasgow, UK"
      ],
      "name": "Srinivasa Vittal Katikireddi"
    }
  ],
  "title": "Incidence of physical non-communicable disease in people who have experienced imprisonment compared with the general population in high-income countries: a systematic review and meta-analysis",
  "uid": "f1738478-b1a8-522a-95df-1ec8129cb62c"
}