{
  "abstract": "Background The transformation of the NHS, outlined in the 10-Year Health Plan for England, must take account of the inexorable rise in the prevalence of multiple long-term conditions (MLTC). However, most evidence on MLTC is based on primary care data preceding the COVID-19 pandemic and, data from hospitals are scarce. We aimed to analyse electronic health records to estimate the prevalence of MLTC among adults accessing hospital care in North East England, and to test associations between sociodemographic characteristics and MLTC.Methods All adults with at least one admission to Newcastle upon Tyne Hospitals NHS Foundation Trust between July 2018 and June 2019 (N= 88,117, 51% women) or between July 2021 and June 2022 (N=83,036, 51% women) were included. MLTC was defined as the presence of ≥2 long-term conditions from a list of 60. Poisson regression models were used to test associations of age, sex, ethnicity and index of multiple deprivation with MLTC.Results Prevalence of MLTC was 49.6% between July 2018 and June 2019 and 61.0% between July 2021 and June 2022. Older age and neighbourhood deprivation were associated with increased risk of MLTC; people living in the most deprived neighbourhoods had a prevalence of MLTC equivalent to people from the least deprived neighbourhoods a decade older. Associations between neighbourhood deprivation and MLTC were stronger in younger adults; those aged 30-39y living in the most deprived neighbourhoods had 1.74 (95% confidence interval: 1.49-2.02) times higher risk of MLTC than those living in the least deprived neighbourhoods.Conclusion Among adults accessing hospital care in NE England, prevalence of MLTC is high, has increased since the COVID-19 pandemic and has a greater impact on younger adults from the most deprived neighbourhoods. This highlights the sheer scale of the challenge that MLTC present in hospitals which must be addressed when redesigning services fit for the future.",
  "authors": [
    {
      "affiliations": [
        "AGE Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK",
        "NIHR Newcastle Biomedical Research Centre, NuTH, CNTW and Newcastle University, Newcastle upon Tyne, UK",
        "Multiple Long-Term Conditions Cross-NIHR Collaboration, UK"
      ],
      "name": "Rachel Cooper"
    },
    {
      "affiliations": [
        "Biostatistics Research Group, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK"
      ],
      "name": "Marzieh Shahmandi"
    },
    {
      "affiliations": [
        "AGE Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK",
        "NIHR Newcastle Biomedical Research Centre, NuTH, CNTW and Newcastle University, Newcastle upon Tyne, UK"
      ],
      "name": "Jonathan Bunn"
    },
    {
      "affiliations": [
        "Digital Services, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK"
      ],
      "name": "Peta Leroux"
    },
    {
      "affiliations": [
        "NIHR Newcastle Biomedical Research Centre, NuTH, CNTW and Newcastle University, Newcastle upon Tyne, UK",
        "Digital Services, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK"
      ],
      "name": "Chris Plummer"
    },
    {
      "affiliations": [
        "Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK"
      ],
      "name": "Tom Marshall"
    },
    {
      "affiliations": [
        "Biostatistics Research Group, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK"
      ],
      "name": "James Wason"
    },
    {
      "affiliations": [
        "AGE Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK",
        "NIHR Newcastle Biomedical Research Centre, NuTH, CNTW and Newcastle University, Newcastle upon Tyne, UK",
        "Multiple Long-Term Conditions Cross-NIHR Collaboration, UK"
      ],
      "name": "Miles Witham"
    },
    {
      "affiliations": [
        "AGE Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK",
        "NIHR Newcastle Biomedical Research Centre, NuTH, CNTW and Newcastle University, Newcastle upon Tyne, UK",
        "Multiple Long-Term Conditions Cross-NIHR Collaboration, UK"
      ],
      "name": "Avan Sayer"
    }
  ],
  "title": "P06-5 What do multiple long-term conditions tell us about the deterioration of health among people accessing hospital care in the North East of England?",
  "uid": "1193d8ed-bc87-57ff-9fdf-5b74ead408f5"
}