{
  "abstract": "Platypnoea–orthodeoxia syndrome (POS), first described in 1949, remains one of the most fascinating examples of positional physiology in cardiovascular medicine. Patients experience dyspnoea and arterial desaturation that worsen when upright and improve when supine. At first glance, the mechanism seems simple: an interatrial communication allows right-to-left shunting. In practice, however, POS is rarely straightforward.",
  "authors": [
    {
      "affiliations": [
        "Division of Cardiovascular Medicine, Department of Internal Medicine, Toho University Faculty of Medicine Graduate School of Medicine, Ota, Tokyo, Japan",
        "Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan"
      ],
      "name": "Mike Saji"
    },
    {
      "affiliations": [
        "Division of Cardiovascular Medicine, Department of Internal Medicine, Toho University Faculty of Medicine Graduate School of Medicine, Ota, Tokyo, Japan"
      ],
      "name": "Hiroshi Ohara"
    }
  ],
  "title": "When a patent foramen ovale becomes pathological",
  "uid": "940d05d7-b1d9-5acc-a4dc-e5b475142045"
}