{
  "abstract": "Cardiac device therapy has significantly evolved since the introduction of the first implantable pacemaker and the subsequent development of the implantable cardioverter-defibrillator (ICD). ICDs are highly effective; however, their main weakness lies in lead-related complications. To avoid the need for venous access and the complications associated with transvenous leads, a fully subcutaneous ICD (S-ICD) system was developed. Despite these advancements, the S-ICD system is limited by its inability to provide bradycardia pacing and antitachycardia pacing. This limitation prompted the development of a modular cardiac rhythm management system, integrating a new leadless pacemaker with an S-ICD that uses unidirectional communication to command the pacemaker to deliver antitachycardia pacing.Conduction system pacing, including His bundle pacing and left bundle branch area pacing (LBBAP), has emerged as a physiological alternative to biventricular resynchronisation therapy and conventional pacing, pending results of large clinical trials. LBBAP offers superior electrical parameters and long-term performance compared with His bundle pacing. The capability to provide defibrillation via the same lead used for LBBAP represents an unresolved challenge that is currently under ongoing research.This state-of-the-art review presents the latest developments and innovations in cardiac device therapy, offering a comprehensive overview of current technologies that increasingly enable therapy to be tailored to individual patient needs.",
  "authors": [
    {
      "affiliations": [
        "Hospital Clinic de Barcelona, Barcelona, Spain",
        "Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain"
      ],
      "name": "Margarida Pujol-Lopez"
    },
    {
      "affiliations": [
        "The University of Arizona College of Medicine-Phoenix, Banner-University Medical Center-Phoenix, Division of Cardiology, Phoenix, Arizona, USA"
      ],
      "name": "Roderick Tung"
    },
    {
      "affiliations": [
        "Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain",
        "Cardiology, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain",
        "Centro de Investigación Biomédica en Red",
        "Enfermedades Cardiovasculares (CIBERCV), Instituto de Salut Carlos III, Madrid, Spain"
      ],
      "name": "Lluis Mont"
    }
  ],
  "title": "Innovations in cardiac device therapy in the era of advanced rhythm management: implantable defibrillators and conduction system pacing",
  "uid": "a9cafd31-5a5a-594c-bb69-aa98b4ab5ff1"
}