{
  "abstract": "Background In 2024, the UK National Institute of Health and Care Excellence (NICE) recommended TriageHF alerts as an option for remote monitoring of patients with heart failure (HF) and a compatible cardiac implantable electronic device (CIED). Data on the cost-effectiveness of this approach has not been published. This research evaluates the cost-effectiveness of TriageHF Plus in public hospital settings, using data from the TriageHF Plus multicentre study (758 participants, NCT04177199).Methods An economic model was developed to capture the lifetime cost and benefits of TriageHF Plus versus usual care, based on a site of 300 eligible patients. Analysis on individual patient-level data informed model efficacy and resource use parameters. EuroQol five-dimensional questionnaire data and unit costs were obtained from published, peer-reviewed literature and national databases respectively. Costs and benefits were discounted at 3.5% per annum to adjust future costs and benefits to present value.Results In a site size of 300, TriageHF Plus was predicted to prevent 384 (363–405) hospitalisations over 5 years. In total, TriageHF Plus saved £3989 (£1812–£5563) per person-lifetime versus usual care and was more effective and cost-saving in 99.4% of simulations. Results were robust to changes in key input parameters. Modelling showed that to avoid one hospitalisation, 1.7 people would need lifetime access to TriageHF Plus.Conclusion The TriageHF Plus pathway is cost-effective for the remote monitoring of HF in patients with CIEDs.Trial registration number NCT04177199.",
  "authors": [
    {
      "affiliations": [
        "Department of Cardiology, Manchester University NHS Foundation Trust, Manchester, UK",
        "Keele Cardiovascular Research Group, Keele University, Newcastle-under-Lyme, UK"
      ],
      "name": "Fozia Z Ahmed"
    },
    {
      "affiliations": [
        "Statistics Department, Research and Innovation, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK",
        "Centre for Biostatistics, University of Manchester, Manchester, UK"
      ],
      "name": "Rachel Harwood"
    },
    {
      "affiliations": [
        "Medtronic, Mounds View, Minnesota, USA"
      ],
      "name": "David Lanctin"
    },
    {
      "affiliations": [
        "Medtronic, Mounds View, Minnesota, USA"
      ],
      "name": "Catherine Leonard"
    },
    {
      "affiliations": [
        "Enterprise House, York Health Economics Consortium Ltd, Heslington, UK"
      ],
      "name": "Sarah Medland"
    },
    {
      "affiliations": [
        "Enterprise House, York Health Economics Consortium Ltd, Heslington, UK"
      ],
      "name": "Daniela Afonso"
    },
    {
      "affiliations": [
        "Enterprise House, York Health Economics Consortium Ltd, Heslington, UK"
      ],
      "name": "Stuart Mealing"
    },
    {
      "affiliations": [
        "Department of Cardiology, Northern Care Alliance NHS Foundation Trust, Manchester, UK"
      ],
      "name": "Toni Weldon"
    },
    {
      "affiliations": [
        "Department of Cardiology, Manchester University NHS Foundation Trust, Manchester, UK"
      ],
      "name": "Callum Blunt"
    },
    {
      "affiliations": [
        "Department of Cardiology, Manchester University NHS Foundation Trust, Manchester, UK",
        "Division of Cardiovascular Sciences, University of Manchester, Manchester, UK"
      ],
      "name": "Niall G Campbell"
    },
    {
      "affiliations": [
        "Department of Cardiology, Manchester University NHS Foundation Trust, Manchester, UK",
        "Division of Informatics, Imaging and Data Sciences, University of Manchester, Manchester, UK"
      ],
      "name": "Joanne K Taylor"
    }
  ],
  "title": "Economic evaluation of the TriageHF Plus clinical pathway for device-based remote monitoring in heart failure",
  "uid": "a1868bc7-30b9-5261-ba35-98a6e80aae71"
}