{
  "abstract": "Introduction Several cardiovascular procedures, like transcatheter aortic valve implantation(TAVI), have shown an obesity paradox. However, limited data exists regarding the impact of body mass index (BMI) on patients undergoing surgical aortic valve replacement(SAVR), particularly among underweight cases. This study aims to conduct a BMI- stratified analysis of short-term outcomes following SAVR.Methods Procedures of SAVR were extracted using the National Inpatient Sample(2016–2022). We stratified our cohort based on BMI into underweight, normal, overweight, and obese. Keeping the normal BMI cohort as a reference, we evaluated the differences in short-term outcomes.Results In this study, we considered 3150(3.7%) patients with normal BMI, while there were 2300(2.7%), 12325(14.3%), and 68425(79.4%) classified as underweight, overweight, and obese respectively. We found that underweight patients had higher odds of sepsis, post-procedural respiratory failure(PPRF), cardiogenic shock(CS), acute kidney injury requiring hemodialysis(AKI+HD), and all-cause mortality than normal BMI cases. Meanwhile, obese and overweight patients expressed lower odds of sepsis, major bleeding, and CS than the normal BMI group. Furthermore, overweight patients also had lower odds of PPRF, and AKI+HD (vs. normal BMI), while obese patients had lower odds of post-procedural cerebrovascular event(PPCE)(vs. normal BMI).Conclusion In patients undergoing SAVR, obese and overweight individuals paradoxically experienced a lower risk for several complications, while underweight patients faced a higher risk.",
  "authors": [
    {
      "affiliations": [
        "Maulana Azad Medical College, New Delhi, India"
      ],
      "name": "Abhinav Malik"
    },
    {
      "affiliations": [
        "Maulana Azad Medical College, New Delhi, India"
      ],
      "name": "Simran Dahiya"
    },
    {
      "affiliations": [
        "Newcastle University Medical School, Newcastle, UK"
      ],
      "name": "Amaad Shah"
    },
    {
      "affiliations": [
        "Maulana Azad Medical College, New Delhi, India",
        "Newcastle University Medical School, Newcastle, UK",
        "DMC/WSU (Sinai-Grace) Hospital, Detroit, Michigan, US",
        "Trinity Health Oakland / Wayne State University, Michigan, US",
        "Trinity Health Livonia Hospital, Livonia, Michigan, US",
        "Overland Park Regional Medical Center, Kansas, US",
        "Independent Researcher, Brampton, Canada",
        "Christus St. Michael Hospital, Texarkana, Texas, US",
        "Independent Researcher, Triolet, Mauritius",
        "National Heart and Lung Institute, Imperial College London, London, UK"
      ],
      "name": "Muhammad Kazmi"
    },
    {
      "affiliations": [
        "DMC/WSU (Sinai-Grace) Hospital, Detroit, Michigan, US"
      ],
      "name": "Nomesh Kumar"
    },
    {
      "affiliations": [
        "Maulana Azad Medical College, New Delhi, India",
        "Newcastle University Medical School, Newcastle, UK",
        "DMC/WSU (Sinai-Grace) Hospital, Detroit, Michigan, US",
        "Trinity Health Oakland / Wayne State University, Michigan, US",
        "Trinity Health Livonia Hospital, Livonia, Michigan, US",
        "Overland Park Regional Medical Center, Kansas, US",
        "Independent Researcher, Brampton, Canada",
        "Christus St. Michael Hospital, Texarkana, Texas, US",
        "Independent Researcher, Triolet, Mauritius",
        "National Heart and Lung Institute, Imperial College London, London, UK"
      ],
      "name": "Harkaran Shergill"
    },
    {
      "affiliations": [
        "Trinity Health Oakland / Wayne State University, Michigan, US"
      ],
      "name": "Fathima Shehnaz Ayoobkhan"
    },
    {
      "affiliations": [
        "Trinity Health Oakland / Wayne State University, Michigan, US"
      ],
      "name": "Vivek Mittal"
    },
    {
      "affiliations": [
        "Trinity Health Livonia Hospital, Livonia, Michigan, US"
      ],
      "name": "Parampreet Johal"
    },
    {
      "affiliations": [
        "Overland Park Regional Medical Center, Kansas, US"
      ],
      "name": "Rutvi Amin"
    },
    {
      "affiliations": [
        "Independent Researcher, Brampton, Canada"
      ],
      "name": "Balkiranjit Kaur Dhillon"
    },
    {
      "affiliations": [
        "Christus St. Michael Hospital, Texarkana, Texas, US"
      ],
      "name": "Hemamalini Sakthivel"
    },
    {
      "affiliations": [
        "Independent Researcher, Triolet, Mauritius"
      ],
      "name": "Kamleshun Ramphul"
    },
    {
      "affiliations": [
        "National Heart and Lung Institute, Imperial College London, London, UK"
      ],
      "name": "Raheel Ahmed"
    }
  ],
  "title": "2-046 Mass index classifications and their associations with short-term outcomes of surgical aortic valve replacement",
  "uid": "ece399b6-0422-5284-a741-26874587de22"
}