{
  "abstract": "The timing of aortic valve replacement (AVR) in asymptomatic patients with severe aortic stenosis has been debated for several decades. Based on observational data and expert opinion, international guidelines recommend a conservative approach with close clinical surveillance. With improvements in surgical AVR and peri-operative care, there has been a trend for more asymptomatic patients to receive AVR and propensity-matched analyses have suggested benefit of early intervention. Furthermore, the advent of transcatheter aortic valve implantation (TAVI) has seen low peri-procedural risk and good medium-term safety data, leading many to question whether asymptomatic patients with severe aortic stenosis should now receive AVR or TAVI?",
  "authors": [
    {
      "affiliations": [
        "Department of Cardiovascular Sciences, University of Leicester, Leicester, UK"
      ],
      "name": "Gerry P McCann"
    },
    {
      "affiliations": [
        "Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, UK"
      ],
      "name": "David E Newby"
    },
    {
      "affiliations": [
        "Department of Cardiology, Royal Perth Hospital, Perth, Western Australia, Australia"
      ],
      "name": "Graham S Hillis"
    }
  ],
  "title": "TAVI for asymptomatic aortic stenosis? More compelling outcome data are needed",
  "uid": "8259b19f-185f-5b6e-87e2-3f636c5e3f04"
}