{
  "abstract": "We read with interest the study by Mantovani et al, which, through a large-scale meta-analysis, revealed that hypothyroidism is associated with an elevated risk of metabolic dysfunction-associated steatotic liver disease (MASLD).1 However, the molecular mechanisms underlying this association remain unclear. Recent large-scale genome-wide association studies (GWAS) have identified novel risk variants associated with hypothyroidism and MASLD.2 3 With their higher statistical power, these large-scale studies offer an important opportunity to elucidate the mechanisms underlying the association between hypothyroidism and MASLD.",
  "authors": [
    {
      "affiliations": [
        "Aging Institute, University of Pittsburgh, Pittsburgh, PA, USA"
      ],
      "name": "Shifang Li"
    },
    {
      "affiliations": [
        "Institute of Translational Medicine, China Pharmaceutical University, Nanjing, People's Republic of China"
      ],
      "name": "Dawei Chen"
    },
    {
      "affiliations": [
        "UPMC Hillman Cancer Center and Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA"
      ],
      "name": "Meijiao Gong"
    }
  ],
  "title": "CTCF-rs705704-SUOX axis is important for the association between hypothyroidism and metabolic dysfunction-associated steatotic liver disease",
  "uid": "5345a129-768f-50cb-9e5c-009ca0f1be99"
}