{
  "abstract": "Background Ulcerative colitis (UC) is a chronic, nonspecific inflammatory disease of the intestine. Atherosclerosis is considered a chronic inflammatory condition of the vascular wall, and its pathogenesis is related to systemic inflammation. UC is closely related to cardiovascular diseases. Cardiac ultrasound has the advantages of being non-invasive, fast, inexpensive, and radiation-free, and can be used to quantitatively assess the extent of cardiovascular involvement in UC patients, predict the risk of cardiovascular diseases and disease progression, thereby guiding early personalized prevention and treatment for UC patients. This study aims to analyze the risk factors for early cardiovascular involvement in UC patients.Methods This study selected 101 UC patients who were continuously treated in the Department of Gastroenterology in our hospital from December 2024 to February 2026 as research subjects. SPSS 25.0 software was used for statistical analysis.Results Age at disease onset and endoscopic Mayo score (MES) were predictive factors for abnormal average e’, with the optimal cutoff value for predicting abnormal e’ being 45 years ( IDDF2026-ABS-0526 Figure 1). Age was an independent predictor of abnormal E/A, with the optimal cutoff value being 57.5 years (IDDF2026-ABS-0526 Figure 2). Modified Mayo score was an independent predictor of left ventricular global longitudinal strain (LVGLS), with the optimal cutoff value being 8.5 points (IDDF2026-ABS-0526 Figure 3). MES was an independent predictor of impaired left atrial conduit strain, and age at disease onset was an independent predictor of left atrial maximum volume index (LAVImax), with the optimal cutoff value being 39.5 years (IDDF2026-ABS-0526 Figure 4). Age and modified Mayo score were independent predictors of abnormal Tricuspid Annular Plane Systolic Excursion (TAPSE); for each one-unit increase in age and modified Mayo score, TAPSE decreased by 0.203 and 0.461 units, respectively (IDDF2026-ABS-0526 Table 1).Conclusions Age, age at onset, endoscopic Mayo score, and modified Mayo score are closely related to early cardiovascular involvement in UC patients.Abstract IDDF2026-ABS-0526 Table 1TAPSEUnstandardized CoefficientStandard coefficienttPmodelBStandard errorBetaConstant28.9072.34112.3460.000Age (year)-0.2030.091-0.474-2.2340.028Age of onset (year)0.0760.0840.1930.9080.366Bowel movement frequency (times/day)0.0690.1490.0630.4600.647Modified Mayo Score-0.4610.176-0.358-2.6140.010Abstract IDDF2026-ABS-0526 Figure 1Abstract IDDF2026-ABS-0526 Figure 2Abstract IDDF2026-ABS-0526 Figure 3Abstract IDDF2026-ABS-0526 Figure 4",
  "authors": [
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Lijie Gao"
    },
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Chenyang Li"
    },
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Haiyan Li"
    },
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Gaojie Han"
    },
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Qian Liu"
    },
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Jia Song"
    },
    {
      "affiliations": [
        "The Second Hospital of Hebei Medical University, China"
      ],
      "name": "Xiaolan Zhang"
    }
  ],
  "title": "IDDF2026-ABS-0526 Correlation analysis of cardiovascular involvement in ulcerative colitis",
  "uid": "f134e238-d47f-59fe-a443-3c14d54db9f1"
}