{
  "abstract": "Introduction Psychological resilience, an individual’s ability to adapt positively to stress or adversity, is a modifiable trait. Low resilience is associated with symptoms of anxiety and depression. Given the negative influence of poor psychological health on the natural history of inflammatory bowel disease (IBD), a better understanding of resilience and its associations at the time of diagnosis may help identify patients who could benefit from early supportive interventions.Methods Consecutive adults (≥18 years) with a new diagnosis of IBD based on endoscopic, histological or radiological findings were recruited at Leeds Teaching Hospitals NHS Trust from March 2023 to September 2025. Demographic, disease-related and psychosocial data were collected. Psychological resilience was assessed via the Connor-Davidson Resilience Scale (CD-RISC), which has been validated in general population samples and divides resilience into quartiles (quartile 1 lowest; quartile 4 highest). Low resilience among IBD patients was defined as scores falling into the lowest quartile of the score. Anxiety and depression symptoms were assessed via the Hospital Anxiety and Depression Scale. Baseline characteristics were summarised and factors associated with low resilience were explored using chi-square tests (SPSS version 31.0).Results In total, 418 patients provided data (mean age 41.8 years, 48.1% females, 82.1% Caucasian, 57.4% married or co-habiting, 54.8% with ulcerative colitis (UC), 32.3% Crohn’s disease, 12.9% IBD unclassified). Overall, 70.0% were in the lowest quartile on the CD-RISC. Those in the higher quartiles were more likely to be older (p<0.001), male (p<0.001) and married or co-habiting (p=0.001). No other baseline characteristics were associated with baseline resilience. Self-reported stressful life events in the 12 months prior to diagnosis of IBD were associated with the lowest quartile (p=0.003), as were symptoms of anxiety and depression (p<0.001 for both) ( figure 1). Disease-related factors including type of IBD, extent, distribution and endoscopic MAYO score for UC were not associated with resilience.Conclusion Among those with newly diagnosed IBD, 70% reported the lowest levels of psychological resilience, which was associated with symptoms of anxiety and depression but not disease-related factors. Future studies should assess whether low resilience at the time of diagnosis has an adverse impact on future IBD outcomes.Abstract P209 Figure 1Resilience level according to the prevalence of symptoms of anxiety and depression",
  "authors": [
    {
      "affiliations": [
        "Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom"
      ],
      "name": "Elaine Ong Ming San"
    },
    {
      "affiliations": [
        "Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom"
      ],
      "name": "Christy Riggott"
    },
    {
      "affiliations": [
        "Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom"
      ],
      "name": "Christian Selinger"
    },
    {
      "affiliations": [
        "Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom"
      ],
      "name": "David Gracie"
    },
    {
      "affiliations": [
        "Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom"
      ],
      "name": "Alex Ford"
    }
  ],
  "title": "P209 Psychological resilience in an inception cohort of patients with inflammatory bowel disease",
  "uid": "ce442b55-724c-5f61-9d03-729379c0bb36"
}