{
  "abstract": "Introduction UK guidelines recommend monitoring the response to therapy in eosinophilic oesophagitis (EOE) to reduce the risk of strictures and complications. Endoscopy and biopsy are gold standard but can be uncomfortable and inconvenient for patients. A prospective cohort study (COSiE) was established to assess the feasibility, efficacy and acceptability of capsule sponge (CS) testing as an alternative. This abstract assess patient experience, tolerability and preference for CS compared with gastroscopy in EOE.Method Adult patients with confirmed EOE were recruited from a dedicated EOE clinic at a UK non-specialist hospital between July 2023 and October 2025. Patients underwent CS testing using the Endosign device the same day prior to gastroscopy. Patients with known oesophageal strictures or recent food bolus obstruction were excluded. Patient feedback was collected before discharge using a single-page questionnaire assessing experience, willingness for CS, pain score using a validated Wong- Baker FACES score and preference for CS or gastroscopy and free field for comments.Results During this period, 134 patients with diagnosed EOE had same day CS and gastroscopy. 181 feedback forms were completed, this included patients who had 2 (n=39) or 3 (n=8) repeat CS., Only 1 form was left uncompleted, 10 patients failed to swallow the CS, and one withdrew consent but still completed feedback. There were 87 (65%) males and 46 (35%) female participants. 93% were white/white British background, 4% Asian, 3% Other. The median age group was 45-64 years and the median age was 54 years old for male and female patients.For those expressing a preference, 127/159 (80%) preferred capsule sponge and 32/159 (20%) preferred gastroscopy. 10 patients expressed no preference and 12 did not complete the question.Of 47 patients who had multiple sponges, 39 (83%) preferred CS and 8 (17%) preferred gastroscopy. Comfort score was measured using Wong-Baker FACES pain score. 77% of patients reported minimal or no pain.Free text comment included themes around speed and ease of CS procedure and mild discomfort rather than pain, a smaller group describing gagging or difficulty in swallowing CS.Conclusion CS is a positive experience for patients and is a preferred option for those requiring monitoring of their EOE activity for most patients with non- stenotic EOE. These results are comparable to previous studies for CS used in investigating patients with Barrett’s oesophagus and reflux which is reassuring given the underlying swallowing problems that are central to EOE patients. CS testing should be made more widely available for EOE patients across the UK: - this will also reduce unnecessary endoscopy and pressure on endoscopy services.Abstract O36 Table 1Pain scorePatient feedback0 – no pain20%257%418%63%81%10 – hurts worst1%",
  "authors": [
    {
      "affiliations": [
        "East And North Hertfordshire Teaching NHS Trust, Stevenage, United Kingdom"
      ],
      "name": "Hyesha McDonald"
    },
    {
      "affiliations": [
        "East And North Hertfordshire Teaching NHS Trust, Stevenage, United Kingdom"
      ],
      "name": "Erzsebet Santa"
    },
    {
      "affiliations": [
        "East And North Hertfordshire Teaching NHS Trust, Stevenage, United Kingdom"
      ],
      "name": "Molly Fifield"
    },
    {
      "affiliations": [
        "East And North Hertfordshire Teaching NHS Trust, Stevenage, United Kingdom"
      ],
      "name": "Kim Shaw"
    },
    {
      "affiliations": [
        "East And North Hertfordshire Teaching NHS Trust, Stevenage, United Kingdom"
      ],
      "name": "Danielle Morris"
    }
  ],
  "title": "O36 Listening to patients - Real world evaluation of capsule sponge monitoring in eosinophilic oesophagitis",
  "uid": "b02a425a-61c1-54af-90c7-f6de46f3758b"
}