{
  "abstract": "Background Gastrointestinal (GI) diseases are common non-motor features of Parkinson’s disease (PD), significantly impacting quality of life. Racial and gender disparities influence these diseases, but their impact remains underexplored. This study examines the association of race and gender with GI syndromes in hospitalized PD patients.Methods A retrospective study using the National Inpatient Sample was conducted, including 124,345 hospitalized PD patients. Multivariable logistic regression was used to assess associations between GI conditions and race/ethnicity (White, Black, Hispanic) and sex, adjusting for confounders.Results Overall prevalence of GI diseases was 49.07%. Compared with White males, Black males had higher odds of dysphagia (aOR 1.27, 95%CI 1.04–1.56), and both Black (aOR 2.19, 95%CI 1.48–3.36) and Hispanic patients (aOR 1.7, 95%CI 1.05–2.77) had significantly higher odds of gastrostomy tube placement. White females had significantly higher odds of gastroesophageal reflux (GERD) (aOR 1.35, 95%CI 1.25–1.46), constipation (aOR 1.34, 95%CI 1.23–1.59), gastroparesis (GP) (aOR 3.44, 95%CI 2.23–5.31), and IBS (aOR 3.1, 95%CI 2.2–4.2), but lower odds of dysphagia (aOR 0.82, 95%CI 0.74–0.91), compared with White males.Conclusion Significant racial and gender disparities were observed in GI diseases among hospitalized PD patients. White females showed higher odds of GERD, constipation, GP, and IBS, while Black and Hispanic patients were more likely to require gastrostomy tube placement. These patterns highlight the need for tailored, equitable care strategies and further research to better understand and address disparities in PD-related GI outcomes.",
  "authors": [
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Mohamed Mahmoud Marey"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Mohamed Eldesouki"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Ahmed Yasser Shaban"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Eslam Mohammed Rabea"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Abdulrhman Helal"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Mohamed Seisa"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Omar Abdelhalim"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Hazem Abosheaishaa"
    },
    {
      "affiliations": [
        "Faculty of Medicine, Alexandria University, Alexandria, Egypt"
      ],
      "name": "Mohamed Khalaf"
    }
  ],
  "title": "P408 Impact of gender and race on gastrointestinal diseases in patients with Parkinson’s disease: a nationwide analysis",
  "uid": "93004988-abb9-5312-9aac-990ad2a73017"
}