{
  "abstract": "Background Frailty is a known contributor to poor outcomes in acute illness. The Eastern Cooperative Oncology Group (ECOG) performance status has been proposed as a practical measure of patient frailty. This study aimed to determine the independent predictive value of ECOG in the setting of upper gastrointestinal bleeding (UGIB).Methods We conducted a retrospective cohort analysis of 1,003 patients who presented with suspected UGIB at a UK tertiary centre and underwent inpatient oesophagogastroduodenoscopy (OGD) between January 2025 and August 2023. The relationship between inpatient mortality and ECOG score was assessed using multivariate logistic regression. The model was adjusted for Glasgow Blatchford Score (GBS), estimated glomerular filtration rate (eGFR), and cancer status variables.Results With a p-value< 0.001, ECOG performance status was proven to be a significant independent predictor of inpatient mortality (aOR 1.529 CI: 1.285–1.820). As expected, other significant predictors for inpatient mortality were GBS and metastatic cancer. Renal function was not statistically significant.Conclusion The ECOG score is a major predictive factor for inpatient mortality, suggesting the importance of frailty assessment in acute UGIB presentations. Standardising the documentation of ECOG may aid in risk stratification and early care escalation decisions.",
  "authors": [
    {
      "affiliations": [
        "Royal Stoke University Hospital, University Hospitals North Midlands, Stoke-On-Trent, United Kingdom"
      ],
      "name": "Mohamed Jalloh"
    },
    {
      "affiliations": [
        "Royal Stoke University Hospital, University Hospitals North Midlands, Stoke-On-Trent, United Kingdom",
        "School of Medicine, Keele University, Stoke-On-Trent, United Kingdom"
      ],
      "name": "Balamrit-Singh Sokhal"
    },
    {
      "affiliations": [
        "Royal Stoke University Hospital, University Hospitals North Midlands, Stoke-On-Trent, United Kingdom"
      ],
      "name": "Maryam Javed"
    },
    {
      "affiliations": [
        "Royal Stoke University Hospital, University Hospitals North Midlands, Stoke-On-Trent, United Kingdom"
      ],
      "name": "Humberto Gomez"
    },
    {
      "affiliations": [
        "Royal Stoke University Hospital, University Hospitals North Midlands, Stoke-On-Trent, United Kingdom"
      ],
      "name": "Jessica Lightfoot"
    },
    {
      "affiliations": [
        "Royal Stoke University Hospital, University Hospitals North Midlands, Stoke-On-Trent, United Kingdom"
      ],
      "name": "Farhan Gohar"
    }
  ],
  "title": "P315 Association between eastern cooperative oncology group performance status and inpatient mortality in upper gastrointestinal bleeding",
  "uid": "60ba5f6d-046d-5b7b-bc3f-c3c6b9c3fb8d"
}