{
  "abstract": "BSG Live’26Introduction Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, yet objective data describing habitual physical activity (PA) in this population are limited. Accurate characterisation of real-world activity patterns is needed, given the health and potential survival benefits of PA in people with cancer.Methods This single-centre prospective cohort study recruited adults with primary liver cancer prior to treatment. Participants wore Axivity AX6 accelerometers to capture habitual physical activity. Self-reported physical activity was assessed using the International Physical Activity Questionnaire–Short Form (IPAQ-SF). Descriptive analyses compared accelerometer-derived and self-reported physical activity.Results A total of 101 patients with primary liver cancer were recruited (median age 72 years, range 49–86; 90% male). The cohort had a high cardiometabolic burden, with a mean body mass index of 30.9 kg/m 2; 52.4% had type 2 diabetes and 58.3% had hypertension. Cirrhosis was present in 55.6% of participants. Most patients had early-stage primary liver cancer at diagnosis.Accelerometer data indicated that a large proportion of the day was spent sedentary, with relatively little time accumulated in higher-intensity activity. Participants spent a mean of 588.6±125.5 min/day sedentary, 249.9±101.5 min/day in light-intensity activity, and 88.2±49.0 min/day in moderate-intensity activity, with vigorous activity negligible.Self-reported physical activity assessed using the questionnaire yielded lower values for sedentary time and light-intensity activity compared with accelerometry. Mean self-reported sedentary time was 456.0±162.0 min/day, approximately 133 min/day lower than accelerometer-derived estimates, while light-intensity activity was 52.7±61.0 min/day, approximately 197 min/day lower. Self-reported moderate-intensity activity (35.1±71.4 min/day) was also lower than accelerometer-derived estimates, whereas vigorous activity was reported (10.9±36.3 min/day) despite being negligible on accelerometry. Overall agreement between self-reported and accelerometer-derived physical activity was poor.Conclusions Patients with primary liver cancer spent a large proportion of the day sedentary and accumulated relatively little time in higher-intensity physical activity, as indicated by accelerometer-derived measures of daily movement behaviour. Self-reported physical activity yielded lower estimates of sedentary time and light- and moderate-intensity activity, and higher estimates of vigorous activity, compared with accelerometry, highlighting substantial differences between measurement approaches. Objective monitoring may therefore complement questionnaire-based assessment by providing an alternative characterisation of habitual activity patterns, with potential relevance for future studies examining physical activity in relation to clinical outcomes.",
  "authors": [
    {
      "affiliations": [
        "National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC), Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Newcastle University Centre for Cancer, Newcastle upon Tyne, United Kingdom"
      ],
      "name": "Helen Reeves"
    },
    {
      "affiliations": [
        "National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC), Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Newcastle University Centre for Cancer, Newcastle upon Tyne, United Kingdom",
        "School of Biomedical, Nutritional and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom"
      ],
      "name": "Nadia Kim"
    },
    {
      "affiliations": [
        "National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC), Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom"
      ],
      "name": "Silvia Del Din"
    },
    {
      "affiliations": [
        "National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC), Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom"
      ],
      "name": "Lisa Alcock"
    },
    {
      "affiliations": [
        "National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC), Newcastle University, Newcastle upon Tyne, United Kingdom",
        "School of Biomedical, Nutritional and Sport Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom",
        "Emles Bioventures, London, United Kingdom"
      ],
      "name": "Samuel T Orange"
    }
  ],
  "title": "P118 Objectively measured physical activity in patients with primary liver cancer",
  "uid": "0eb7be65-0310-53a3-8844-1ea89486d018"
}