{
  "abstract": "We thank Drs O’Grady and colleagues for their interest1 in our commentary ‘Are functional dyspepsia and gastroparesis really ‘interchangeable’ diseases?’2 and their comment agreeing that improvement in tests of gastric emptying (GE) is highly desirable. Their plea for moving the field to understanding mechanisms and validating actionable biomarkers3 with the objective of personalising therapy4 is certainly consistent with our long track record. Consistent with the quest for pathophysiological characterisation of patients with symptoms considered to be arising in the stomach and duodenum, we previously published data on 1287 patients evaluated in the clinical practice using the non-invasive, validated measurements of GE of solids (GES) using the 320 kcal 30% fat chicken egg meal, and gastric accommodation (GA) following 300 mL (and kcal) liquid nutrient drink. We reported 29.8% patients with normal GE and GA, 21.9% abnormal GA only, 27.1% abnormal GE only and 21.1% with abnormal GA and GE.5 We suggested that the first subgroup likely had increased gastroduodenal sensitivity.",
  "authors": [
    {
      "affiliations": [
        "Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA"
      ],
      "name": "Michael Camilleri"
    },
    {
      "affiliations": [
        "School of Medicine and Public Health, The University of Newcastle, Newcastle, New South Wales, Australia"
      ],
      "name": "Nicholas J Talley"
    }
  ],
  "title": "Response to: ‘Differentiating gastroparesis from functional dyspepsia is no longer sufficient’ by O’Grady et al",
  "uid": "fe15e452-f0dc-5241-bd3f-2da861a8f401"
}