{
  "abstract": "A 52-year-old man presented with a 6-month history of diarrhoea and unintentional weight loss of 20 kg. During this period, he reported 2–3 daily episodes of watery stools with intermittent epigastric distension. On admission, his body mass index (BMI) was 14.9 kg/m² (height 1.65 m; weight 40.5 kg). He was not on any chronic medications. Laboratory investigations revealed haemoglobin of 90 g/L, serum total protein of 47.1 g/L and albumin of 22.6 g/L. C reactive protein was 73.3 mg/L. Immunoglobulin M (IgM) was 34.5 g/L (normal range: 0.5–2.2 g/L) and β2-microglobulin was 4949 ng/mL (normal range: 955–2157 ng/mL). White blood cell count, platelets, coagulation profile, renal function and lactate dehydrogenase were unremarkable. Anti-nuclear antibody, extractable nuclear antigen panel and the interferon-gamma release assay were negative. Urinalysis was negative for protein. Stool tests showed calprotectin 110 µg/g (normal range: 0–75 µg/g), positive occult blood and negative cultures. The abdominal CT scan showed no significant abnormalities. Gastroscopy revealed diffuse white patch-like lesions in the duodenum ( figure 1A). Colonoscopy showed diffuse whitish nodularities in the terminal ileum (figure 1B). Capsule endoscopy showed similar lesions in the jejunum and ileum as seen in the duodenum and terminal ileum (figure 1C,D).",
  "authors": [
    {
      "affiliations": [
        "Gastroenterology, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu, China"
      ],
      "name": "Tingting Cao"
    },
    {
      "affiliations": [
        "Gastroenterology, The Affiliated Huaian No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu, China"
      ],
      "name": "Honggang Wang"
    }
  ],
  "title": "Cause of chronic diarrhoea",
  "uid": "e30fa5b0-28b6-5496-968d-01d08d9594da"
}